Results 31 to 40 of about 475,391 (309)
The Age of Migration Crisis [PDF]
Tempo, 2019 Abstract: The article analyzes the historical changes in the formulation of migration policies between the 19th and 21st centuries, summarizing the emergency of an “age of migration crisis”. The first section discusses why international migration poses a destabilizing problem for the Nation-state political conceptions. The second section emphasizes the
openaire +4 more sources
Hyper-legalisation and delegalisation in the AFSJ: on contradictions in the external management of EU migration [PDF]
, 2019 The EU governance of migration has distinct internal and external facets, which may be viewed as innately contradictory. On the one hand, for example, there is legal competence for enhanced measures to combat illegal immigration but on the other hand, it
Fahey, E.
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
, 2014 Crisis and migration have a long association, in popular and policy discourse as well as in social scientific analysis. Despite the emergence of more nuanced and even celebratory accounts of mobility in recent years, there remains a persistent emphasis on migration being either a symptom or a cause of crisis. Moreover, in the context of a recent series
openaire +1 more source
BALTIC TRIPLETS? OUT-MIGRATION MIGRATION AND RESPONSES TO CRISIS [PDF]
Regional Formation and Development Studies, 2021 This article addresses intersections of migration and economic development as one of the most topical contemporary challenges inthe Baltic states. It uses empirical approach to compare governmental responses to recent economic crisis starting in 2008.
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FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Migration, Remittances and the Current Economic Crisis: Implications for Central and Eastern Europe [PDF]
, 2009 In recent years labour migration from Central and Eastern Europe has increased, resulting in a comparatively stable and high inflow of remittances into these countries.
Barbara Dietz
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source