Results 91 to 100 of about 9,780,143 (300)

Classification of socio‐economic factors of spatial heterogeneity affecting migration flows

Векторы благополучия: экономика и социум
The article is devoted to the generalization and clarification of the classification of factors affecting migration flows. In modern conditions of migration activity strengthening, the study of socio‐economic factors that form spatial heterogeneity of ...
A.A. Bychkova
doaj   +1 more source

FACTORS OF NON-MIGRATION AS AN ELEMENT OF MIGRATION PROCESSES MANAGEMENT

Society and Security Insights, 2022
Based on the provisions of migrants’ aspirations/abilities model, it is offered to use the main elements of migration scheme to examine non-migration mechanism. A scheme of migration action is presented on the basis of migration factors analysis. In addition to taking into account migration factors the authors offer to estimate factors having impact on
openaire   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Migration as cause and consequence of aspirations : DEMIG project paper no. 13 [PDF]

, 2012
This paper aims to disentangle the relationship between aspirations and migration by analysing why Indonesian internal migrants generally have higher aspirations when compared with non-migrants.
Czaika, Mathias
core  

The effect on cardiovascular risk factors of migration from rural to urban areas in Peru [PDF]

During the 20 years of political violence in Peru starting in the late 1970’s, Ayacucho, an Andean department, was one of the most severely affected areas.
Miranda Montero, Juan Jaime
core   +1 more source

Home on the Range: Factors Explaining Partial Migration of African Buffalo in a Tropical Environment [PDF]

, 2012
Partial migration (when only some individuals in a population undertake seasonal migrations) is common in many species and geographical contexts. Despite the development of modern statistical methods for analyzing partial migration, there have been no ...
Du Preez, Pierre, Jago Mark, Naidoo, Robin, Pierre Du Preez, Stuart-Hill Greg, Wegmann, Martin, Mark Jago (159459), Robin Naidoo, Wegmann Martin, Greg Stuart-Hill (166802), Jago, Mark, Martin Wegmann, Naidoo Robin, Robin Naidoo (166788), Mark Jago, Martin Wegmann (166813), Stuart-Hill, Greg, Du Preez Pierre, Greg Stuart-Hill, Pierre Du Preez (166795)   +19 more
core   +2 more sources

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source