Results 111 to 120 of about 695,851 (315)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

The change of normative gender orders in the process of migration. A transnational perspective

, 2008
Jungwirth I. The change of normative gender orders in the process of migration. A transnational perspective. COMCAD Arbeitspapiere - working papers, 48.
Jungwirth, Ingrid
core  

Informal but Effective: Regional Consultative Processes as a Tool in Managing Migration

, 2001
During the 1990s, the number of regional consultative processes focusing on migration increased significantly. These non-binding fora brought together representatives of States, civil society and international organizations at the regional level to ...
von Koppenfels, Amanda Klekowski
core   +1 more source

PMMP-PQC Migration Management Process✱

European Interdisciplinary Cybersecurity Conference
Organizations have to plan on migrating to quantum-resilient cryptographic measures, also known as PQC. However, this is a difficult task, and to the best of our knowledge, there is no generalized approach to manage such a complex migration for cryptography used in IT systems that explicitly integrates into organizations' steering mechanisms and ...
Nils von Nethen, Alexander Wiesmaier, Nouri Alnahawi, Johanna Henrich   +3 more
openaire   +2 more sources

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

The migration flux: Understanding international immigration through internal migration [PDF]

This paper introduces the idea that the network structure that emerges from a foreign-born population's internal migration process changes the conditions for international immigration.
Rickard Sandell
core  

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Migration decision-making processes: an empirical investigation. [PDF]

This thesis has two purposes. The first is to investigate the motivation for householdmigration - in particular, the associations between the different reasons for movingand the characteristics of owner-occupier movers in Scotland, their houses and ...
Forster, Emma
core  

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source