Results 131 to 140 of about 695,851 (315)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Migration and first-time parenthood [PDF]

open access: yes
This article investigates the reproductive behavior of young women and men in the post-Soviet Central Asian republic of Kyrgyzstan, focusing on the link between migration and fertility.
Gunnar Andersson, Lesia Nedoluzhko
core  

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Leaving matters: the nature, evolution and effects of emigration policies: DEMIG project paper no. 4

open access: yes, 2011
Debates on migration policies are strongly focused on immigration control, revealing a general receiving-country bias in migration research. To fill this gap, this paper reviews the nature, evolution and effects of emigration policies.
Vezzoli, Simona, de Haas, Hein
core  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Migration system formation and decline: a theoretical inquiry into the self-perpetuating and self-undermining dynamics of migration processes

open access: yes, 2009
The migration literature has identified various mechanisms which explain why, once started, migration processes tend to gain their own momentum and become self-perpetuating, partly independent of their original causes, leading to the formation of ...
de Haas, Hein
core  

Scientific approaches to the study of migration

open access: yesХабаршы. Заң сериясы, 2016
The article analyzes the scientific approaches to the study of migration. Migration – a complex and multidimensional phenomenon. This makes studying it in terms interdisciplinary approach to display the breadth of the spectrum of its ...
Dzhansarayeva R.Ye.
doaj  

Vulnerability, Digital Technologies and International Law: Reflections on Contemporary Migration Flows

open access: yesLaw, Technology and Humans
Migration, considered a ‘total social fact’, remains one of the most debated topics in contemporary society. Unfortunately, migration is not always a positive experience for everyone.
Maria Rita Bartolomei, Antonia Cava
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Migration and development in sub-Saharan Africa

open access: yes, 2011
Migration in sub-Saharan Africa, as in the rest of the world, has always been an essential element in the historical processes of social, political and economic change.
Bakewell, Oliver
core  

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