Results 131 to 140 of about 695,851 (315)
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Migration and first-time parenthood [PDF]
This article investigates the reproductive behavior of young women and men in the post-Soviet Central Asian republic of Kyrgyzstan, focusing on the link between migration and fertility.
Gunnar Andersson, Lesia Nedoluzhko
core
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Leaving matters: the nature, evolution and effects of emigration policies: DEMIG project paper no. 4
Debates on migration policies are strongly focused on immigration control, revealing a general receiving-country bias in migration research. To fill this gap, this paper reviews the nature, evolution and effects of emigration policies.
Vezzoli, Simona, de Haas, Hein
core
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
The migration literature has identified various mechanisms which explain why, once started, migration processes tend to gain their own momentum and become self-perpetuating, partly independent of their original causes, leading to the formation of ...
de Haas, Hein
core
Scientific approaches to the study of migration
The article analyzes the scientific approaches to the study of migration. Migration – a complex and multidimensional phenomenon. This makes studying it in terms interdisciplinary approach to display the breadth of the spectrum of its ...
Dzhansarayeva R.Ye.
doaj
Migration, considered a ‘total social fact’, remains one of the most debated topics in contemporary society. Unfortunately, migration is not always a positive experience for everyone.
Maria Rita Bartolomei, Antonia Cava
doaj +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Migration and development in sub-Saharan Africa
Migration in sub-Saharan Africa, as in the rest of the world, has always been an essential element in the historical processes of social, political and economic change.
Bakewell, Oliver
core

