Results 101 to 110 of about 120,916 (311)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Atlas sur les migrations internationales
, 2009 Dossier 2ème partie : OutilsInternational audiencePour compléter l'article, disponible dans ce même numéro, sur les documents cartographiques sur les migrations internationales présents sur Internet, nous proposons une bibliographie commentée consacrée ...
Bahoken, Françoise
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Symmetry and tendency judgment of Ms ≥ 8.0 strong earthquakes in Chile
Geodesy and Geodynamics, 2014 The Ms ≥8.0 strong earthquakes occurring in Chile since 1800 were analyzed using the ternary, quaternary, and quinary commensurability methods and the butterfly structure diagram, and it was believed that the earthquake signal in Chile in 2014 is ...
Jin Junfang, Yin Shuyan, Yan Junping
doaj +1 more source
Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
Molecular Oncology, EarlyView.LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
, 2021 This chapter discusses the importance of a gender perspective on international migration. It shows that gender impacts migration decision making, individual experiences of migration, and immigration policies. The chapter starts by outlining the gendered composition of migration flows and stocks, noting that the share of male and female migrants is ...
Bonjour, S., Cleton, L.
openaire +3 more sources
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
, 2015 Présentation de l’atelier Créé en 2006 afin de réfléchir aux problématiques liées aux migrations (au sens large), l’atelier Migrations regroupe des jeunes chercheurs (doctorant-e-s, post-doctorant-e-s et masterant-e-s) en sciences sociales (sociologie ...
ninasahraoui
core
, 2018 This commentary brings my personal migration story to bear on our shifting understanding of both queers and migrants into the realm of contemporary art practice.
Gupta, S.
core +1 more source