Results 111 to 120 of about 120,916 (311)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

What is “Music migrations”?

, 2013
The investigation of music migrations will offer insight into musico-cultural encounters, in spatial terms (European East, West and South), and in temporal terms (17th-18th c., i.e. Baroque and Classicism).
Martin Albrecht-Hohmaier
core  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

"CATÓLICOS, APOSTÓLICOS Y NO-SATÁNICOS ": REPRESENTACIONES CONTEMPORÁNEAS EN MÉXICO Y CONSTRUCCIONES LOCALES (VERACRUZ) DEL CULTO A LA SANTA MUERTE.

Revista Cultura & Religión, 2014
Este artículo, mediante un enfoque basado en un cuestionamiento de la oposición clásica entre religión institucional y religiosidad popular, propone analizar la manera en que los devotos del culto a la Santa Muerte, en interacción con los medios de ...
Kali Argyriadis
doaj  

Lorsque le contrôle des migrations prend le pas sur la sauvegarde de la vie en mer : l’émergence des frontières dans la zone de responsabilité SAR espagnole

Criminologie
Selon les conventions internationales régissant le sauvetage en mer, les frontières maritimes ne doivent pas interférer avec les opérations de sauvetage en mer, la sauvegarde de la vie en mer étant définie comme prioritaire. Pourtant, depuis 2015 et dans
Arnaud Banos, Luna Vives, Camille Martel, Elizabeth Hessek, Kira Williams   +4 more
doaj   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Londres et ses migrations

, 2019
À l’occasion de l’exposition Paris-Londres, Music migrations, la revue explore la manière dont Londres, ancienne métropole d’empire, est devenue un des principaux carrefours migratoires de l’Europe.
Bensignor, François, Wihtol de Wenden, Catherine, Beaugrand, Claire, Kone, Zovanga, Lacroix, Thomas, Alexandre, Stéphanie, Sarr, Mohamed Mbougar, Cavaniol, Hubert, Jnaid, Nihad, Jolys-Shimells, Elisabeth, Bocard, Hélène, Broadhead, Jacqueline, Volery, Anne, Bousquet, David, Evans, Martin, Harzoune, Mustapha, Consterdine, Erica, Meflah, Nadia, Poinsot, Marie, Vargas - Silva, Carlos, Robinson, Lucy, Lostis, Nina, Collyer, Michael   +22 more
core   +1 more source

Editorial

, 1987
Revue Hommes et Migrations. Editorial. In: Hommes et Migrations, n°1103, mai 1987. pp.
Hommes & Migrations
core   +2 more sources