Results 31 to 40 of about 325,848 (294)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

[Review of] Hoerder, Dirk. Cultures in Contact: World Migrations in the Second Millennium [PDF]

, 2003
Cultures in Contact is an ambitious tome of the annotated world history of human mass migrations both within and between national boundaries. This book provides a glorious descriptive wealth of when, where, and to a lesser extent why mass migrations ...
Bulk, Jac D.
core   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

“We Speak the Same Language, but They Don't Understand Us.” Use and Abuse of Culturalism in Medical Care for Central American Migrants in Transit Through Mexico

Frontiers in Public Health, 2022
This article deals with cultural stereotypes toward Central American migrants in the Mexican healthcare system, which lead to the naturalization of the supposed cultural characteristics of these new users.
Philippe Stoesslé, Philippe Stoesslé, Philippe Stoesslé   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Towards a regional agreement on environmental displacement?

Forced Migration Review, 2017
Efforts towards a regional agreement on migration in South America should be extended to recognise and protect those displaced for environmental reasons.
Erika Pires Ramos, Fernanda de Salles Cavedon-Capdeville, Lilian Yamamoto, Diogo Andreola Serraglio   +3 more
doaj  

Écrire les voix d'autres personnes : entre engagements, trahisons et réciprocités

Nouvelle Revue Synergies Canada, 2022
Dans le cadre d’une recherche en sciences humaines et sociales, collecter et transcrire des récits de personnes migrantes, par une démarche compréhensive, peut produire un effacement de leurs voix, quand bien même c’est le contraire qui serait visé ...
Delphine Leroy
doaj  

L'organisation spatiale de la fécondité dans les agglomérations : le cas de la Suisse : 1989–1992 [PDF]

Geographica Helvetica
Les comportements de fécondité des communes des grandes agglomérations varient en fonction de la position géographique. L'exemple des 5 grandes villes suisses et des communes qui les entourent montre des caractéristiques clairement définies, quelle que ...
P. Wanner
doaj   +1 more source

Return Migration

Online Readings in Psychology and Culture, 2016
This article aims to present an overview of the literature on return migration. Through combining the perspectives of various disciplines, notably economy, sociology, and psychology, the main theoretical issues, studies and findings in the field of remigration are presented.
Kunuroglu, Filiz, van de Vijver, Fons, Yagmur, Kutlay   +2 more
openaire   +4 more sources