Results 71 to 80 of about 37,657 (265)
The prohibition of the full-face veil in Belgium: between collective hysteria and symbolic policy
Revista CIDOB d'Afers Internacionals, 2017 This article analyses the debate on the prohibition of the full-face veil in Belgium, which was finalised in a law approved in March 2010 by the Belgian Chamber of Representatives after a discussion process in the public sphere and Parliament. First, the
Corinne Torrekens
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Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Venezuelan displacement: a challenge to Brazil
Forced Migration Review, 2017 Brazil must strengthen its reception and integration of fleeing ...
Helisane Mahlke, Lilian Yamamoto
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La frontière étatique, terme de l’aide humanitaire ? Une analyse du droit en action
CriminologieDepuis la décision du Conseil constitutionnel français du 6 juillet 2018 sur la « fraternité », un acte humanitaire désintéressé est licite s’il est cantonné au territoire national et illicite s’il constitue une aide à l’entrée irrégulière sur ce ...
Bastien Charaudeau Santomauro
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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Mobilités étudiantes et territoires universitaires : vers une uniformisation des pratiques ?
Espace populations sociétés, 2005 Since French Society enters the so-called “Economy of knowledge”, migrations of young people, especially these concerning students, are of most interest. Despite the fact that it could help to understand University as a system and ways regions can evolve,
Myriam Baron, Cathy Perret
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Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Symmetry and tendency judgment of Ms ≥ 8.0 strong earthquakes in Chile
Geodesy and Geodynamics, 2014 The Ms ≥8.0 strong earthquakes occurring in Chile since 1800 were analyzed using the ternary, quaternary, and quinary commensurability methods and the butterfly structure diagram, and it was believed that the earthquake signal in Chile in 2014 is ...
Jin Junfang, Yin Shuyan, Yan Junping
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Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
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