Results 41 to 50 of about 5,413 (180)

Microinvasive Glaucoma Surgical Training in United States Ophthalmology Residency Programs

Clinical Ophthalmology, 2020
Cindi K Yim,1,2 Christopher C Teng,3 Joshua L Warren,4 James C Tsai,2 Nisha Chadha2 1USC Roski Eye Institute, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA; 2Department of Ophthalmology, Icahn School of Medicine ...
Yim CK, Teng CC, Warren JL, Tsai JC, Chadha N   +4 more
doaj  

AI‐Driven Cancer Multi‐Omics: A Review From the Data Pipeline Perspective

Advanced Intelligent Discovery, EarlyView.
The exponential growth of cancer multi‐omics data brings opportunities and challenges for precision oncology. This review systematically examines AI's role in addressing these challenges, covering generative models, integration architectures, Explainable AI for clinical trust, clinical applications, and key directions for clinical translation.
Shilong Liu, Shunxiang Li, Kun Qian
wiley   +1 more source

MIGS: miRNA-induced gene silencing

, 2012
Gene silencing is an important tool in the study of gene function. Virus-induced gene silencing (VIGS) and hairpin RNA interference (hpRNAi), both of which rely on small interfering RNAs, together with artificial microRNAs (amiRNA), are amongst the most ...
Weigel, D., Felipe Fenselau de Felippes, Fenselau de Felippes, F., Detlef Weigel, Wang, J., Jia-wei Wang   +5 more
core   +1 more source

A Comparison of Endothelial Cell Loss in Combined Cataract and MIGS (Hydrus) Procedure to Phacoemulsification Alone: 6-Month Results [PDF]

, 2015
Purpose. To compare the corneal endothelial cell loss after phacoemulsification, alone or combined with microinvasive glaucoma surgery (MIGS), in nonglaucomatous versus primary open angle glaucoma (POAG) eyes affected by age-related cataract. Methods. 62
Paola Maria Loredana Cannizzo, Fea, Antonio Maria, Giulia Pignata, Carlo Lavia, Cannizzo, Paola Maria Loredana, Rolle, Teresa, Giulia Consolandi, Pignata, Giulia, Filippo Billia, Grignolo, Federico, Federico M. Grignolo, Teresa Rolle, Consolandi, Giulia, Antonio M. Fea, Lavia, Carlo Alessandro   +14 more
core   +1 more source

Fluorinated Iminosugar Glycomimetics: Synthesis and Activity as GCase Ligands

European Journal of Organic Chemistry, EarlyView.
DAST‐mediated deoxyfluorination of suitably functionalized piperidines provided regio‐ and stereoselective access to fluorinated piperidine and pyrrolidine glycomimetics, the latter arising from an unusual ring‐contraction process. Fluorination generally enhanced β‐glucocerebrosidase (GCase) inhibitory potency, but lost PC activity toward L444P/L444P ...
Francesca Mangiavacchi, Alessio Morano, Cosimo Margheri, Cristina Faggi, Amelia Morrone, Camilla Matassini, Francesca Clemente, Andrea Goti, Martina Cacciarini, Francesca Cardona   +9 more
wiley   +1 more source

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

Investigation of a miRNA-Induced Gene Silencing Technique in Petunia Reveals Alterations in miR173 Precursor Processing and the Accumulation of Secondary siRNAs from Endogenous Genes.

PLoS ONE, 2015
MIGS (miRNA-induced gene silencing) is a straightforward and efficient gene silencing technique in Arabidopsis. It works by exploiting miR173 to trigger the production of phasiRNAs (phased small interfering RNAs).
Yao Han, Bin Zhang, Xiaoting Qin, Mingyang Li, Yulong Guo   +4 more
doaj   +1 more source

GlaucoMap – Distribution of Glaucoma Surgical Procedures in the United States

Clinical Ophthalmology, 2020
Anthony K Ma,1 Jun Hui Lee,1 Joshua L Warren,2 Christopher C Teng3 1Yale School of Medicine, New Haven, CT, USA; 2Department of Biostatistics, Yale School of Public Health, New Haven, CT, USA; 3Department of Ophthalmology and Visual Science, Yale School ...
Ma AK, Lee JH, Warren JL, Teng CC
doaj  

Cross‐Platform Concordance Between Metagenomic and Targeted DNA Sequencing for Diagnosing Polymicrobial Infections in an Immunosuppressed Patient: A Case Report

Medicine Advances, EarlyView.
An immunosuppressed 40‐year‐old man developed rapidly progressive polymicrobial pneumonia caused by Pneumocystis jirovecii and carbapenem‐resistant Klebsiella pneumoniae. Three metagenomic next‐generation sequencing (mNGS) and targeted next‐generation sequencing (tNGS) workflows with different assay designs and technical parameters consistently ...
Mengxia Wang, Jielun Wen, Liyue Sun
wiley   +1 more source

Evolving Sacrocolpopexy Technique Trends

Neurourology and Urodynamics, EarlyView.
ABSTRACT Introduction Sacrocolpopexy (SCP) is widely considered the gold standard procedure for repairing apical and multi‐compartment prolapse. Despite its long‐standing and widespread use, significant technical variations persist, yet these differences have not been well‐characterized or linked to surgical outcomes.
Christina Sze, Carolina Martinez Fernandez, Gabriel Andino, Maali LaFrance Frater, Stephanie Sansone, Sonia Bhandari Randhawa, Gary E. Lemack, Ramy Goueli, Maude Carmel   +8 more
wiley   +1 more source