Results 51 to 60 of about 46,858 (301)

Mike Mansfield Interview, July 21, 2000 [PDF]

, 2000
Mike Mansfield discusses his Navy career and his military experiences during and after World War One. He talks about his relations with the Anaconda Company and the Montana Power Company, noting he had little interaction with them.
Mansfield, Mike
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Numerical model in water quality: The case study of Da Nang City in central Vietnam

River
The planning and treatment of wastewater discharged into rivers and seas is vital for tourism, domestic water supply, and other key sectors. This study used the MIKE 21 model to evaluate water quality trends and the assimilative capacity of the Vu Gia ...
Doan Thuy Kim Phuong, Vo Ngoc Duong, Nguyen Trung Quan, Nguyen Cong Phong, Doan Thi Ngoc Canh   +4 more
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Relaunching the G20 [PDF]

, 2013
Australia and the world needs a focused and effective G20. But the forum is in danger of losing its way. This Analysis identifies nine key lessons from the G20’s history that can help relaunch it. This should be Australia’s goal when it chairs the G20 in
Mike Callaghan
core  

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Simulation of floods under the influence of effective factors in hydraulic and hydrological models using HEC-RAS and MIKE 21

Discover Water
Simulating floods and creating vulnerability maps are essential in urban watershed management systems. The present research aimed to simulate floods and assess floodplain risk in the Khalkai watershed located in Gilan Province, Iran.
Sara Ansarifard, Morteza Eyvazi, Mahsa kalantari, Behrooz mohseni, Mahdi Ghorbanifard, Hadi Jafakesh Moghaddam, Maryam Nouri   +6 more
doaj   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

Analisis Pengaruh Bangunan Krib terhadap Kecepatan Aliran pada Tikungan Luar Sungai Kalibuntu menggunakan Pemodelan Numerik

Jurnal Teknik Hidraulik
River morphology is a condition that is constantly changing due to erosion and sedimentation in certain parts of the river. However, erosion and sedimentation that occur in undesirable parts of the river can cause significant losses to humans.
Salsabila Rifdah Taufik, Bagas Nathanie, Elkayoan Radita, Ririn Rimawan   +3 more
doaj   +1 more source

Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati, Sami I. Nassar, Shaun A. Nguyen, Patricia L. Gerend, Michael C. Schubert, Michael T. Teixido, Frederick A. Godley, Joel A. Goebel, Cynthia A. Ryan, Habib G. Rizk, Amir Kheradmand   +10 more
wiley   +1 more source