Results 11 to 20 of about 740,817 (339)

An extensive disulfide bond network prevents tail contraction in Agrobacterium tumefaciens phage Milano

Nature Communications
A contractile sheath and rigid tube assembly is a widespread apparatus used by bacteriophages, tailocins, and the bacterial type VI secretion system to penetrate cell membranes. In this mechanism, contraction of an external sheath powers the motion of an
Ravi R. Sonani, Lee K. Palmer, Nathaniel C. Esteves, Abigail A. Horton, Amanda L. Sebastian, Rebecca J. Kelly, Fengbin Wang, Mark A. B. Kreutzberger, William K. Russell, Petr G. Leiman, Birgit E. Scharf, Edward H. Egelman   +11 more
doaj   +2 more sources

ApoA-I Milano stimulates lipolysis in adipose cells independently of cAMP/PKA activation

Journal of Lipid Research, 2015
ApoA-I, the main protein component of HDL, is suggested to be involved in metabolic homeostasis. We examined the effects of Milano, a naturally occurring ApoA-I variant, about which little mechanistic information is available.
Maria Lindahl, Jitka Petrlova, Jonathan Dalla-Riva, Sebastian Wasserstrom, Catarina Rippe, Joan Domingo-Espin, Dorota Kotowska, Ewa Krupinska, Christine Berggreen, Helena A. Jones, Karl Swärd, Jens O. Lagerstedt, Olga Göransson, Karin G. Stenkula   +13 more
doaj   +2 more sources

A Walkability Index including Pedestrians’ Perception of Built Environment: The Case Study of Milano Rogoredo Station

Sustainability, 2023
Active modes can play a key role in the transition toward sustainable urban mobility, and transport systems should be designed to support and incentivize them. For instance, walking accessibility to main urban centralities is a factor to pay attention to,
Marco Trolese, Francesco De Fabiis, Pierlugi Coppola   +2 more
semanticscholar   +1 more source

The novel Mechanical Ventilator Milano for the COVID-19 pandemic [PDF]

The Physics of Fluids, 2020
This paper presents the Mechanical Ventilator Milano (MVM), a novel intensive therapy mechanical ventilator designed for rapid, large-scale, low-cost production for the COVID-19 pandemic.
A. Abba, C. Accorsi, P. Agnes, E. Alessi, P. Amaudruz, A. Annovi, F. A. Desages, S. Back, C. Badia, J. Bagger, V. Basile, G. Batignani, A. Bayo, B. Bell, M. Beschi, D. Biagini, G. Bianchi, S. Bicelli, D. Bishop, T. Boccali, A. Bombarda, S. Bonfanti, W. Bonivento, M. Bouchard, M. Breviario, S. Brice, R. Brown, J. M. Calvo-Mozota, L. Camozzi, M. Camozzi, A. Capra, M. Caravati, M. Carlini, A. Ceccanti, B. Celano, J. Cela Ruiz, C. Charette, G. Cogliati, M. Constable, C. Crippa, G. Croci, S. Cudmore, C. Dahl, A. Dal Molin, M. Daley, C. Di Guardo, G. D’Avenio, O. Davignon, M. del Tutto, J. de Ruiter, A. Devoto, P. Diaz Gomez Maqueo, F. Di Francesco, M. Dossi, E. Druszkiewicz, C. Duma, E. Elliott, D. Farina, C. Fernandes, F. Ferroni, G. Finocchiaro, G. Fiorillo, R. Ford, G. Foti, R. Fournier, D. Franco, C. Fricbergs, F. Gabriele, C. Galbiati, P. Garcia Abia, A. Gargantini, L. Giacomelli, F. Giacomini, F. Giacomini, L. Giarratana, S. Gillespie, D. Giorgi, T. Girma, R. Gobui, D. Goeldi, F. Golf, P. Gorel, G. Gorini, E. Gramellini, G. Grosso, F. Guescini, E. Guêtre, G. Hackman, T. Hadden, W. Hawkins, K. Hayashi, A. Heavey, G. Hersak, N. Hessey, G. Hockin, K. Hudson, A. Ianni, C. Ienzi, V. Ippolito, C. C. James, C. Jillings, C. Kendziora, S. Khan, E. Kim, M. King, S. King, A. Kittmer, I. Kochanek, J. Kowalkowski, R. Krücken, M. Kushoro, S. Kuula, M. Laclaustra, G. Leblond, L. Lee, A. Lennarz, M. Leyton, X. Li, P. Liimatainen, C. Lim, T. Lindner, T. Lomonaco, P. Lu, R. Lubna, G. Lukhanin, G. Luzón, M. MacDonald, G. Magni, R. Maharaj, S. Manni, C. Mapelli, P. Margetak, L. Martin, S. Martin, M. Martínez, N. Massacret, P. McClurg, A. Mcdonald, E. Meazzi, R. Migalla, T. Mohayai, L. Tosatti, G. Monzani, C. Moretti, B. Morrison, M. Mountaniol, A. Muraro, P. Napoli, F. Nati, C. Natzke, A. Noble, A. Norrick, K. Olchanski, A. O. D. Ortiz de Solórzano, F. Padula, M. Pallavicini, I. Palumbo, E. Panontin, N. Papini, L. Parmeggiano, S. Parmeggiano, K. Patel, A. Patel, M. Paterno, C. Pellegrino, Patrizio Pelliccione, V. Pesudo, A. Pocar, A. Pope, S. Pordes, F. Prelz, O. Putignano, J. Raaf, C. Ratti, M. Razeti, A. Razeto, D. Reed, J. Refsgaard, T. Reilly, A. Renshaw, F. Retriere, E. Riccobene, D. Rigamonti, A. Rizzi, J. Rode, J. Romualdez, L. Russel, D. Sablone, S. Sala, D. Salomoni, P. Salvo, A. Sandoval, E. Sansoucy, R. Santorelli, C. Savarese, E. Scapparone, T. Schaubel, S. Scorza, M. Settimo, B. Shaw, S. Shawyer, A. Sher, A. Shi, P. Skensved, A. Slutsky, B. Smith, N. Smith, A. Stenzler, C. Straubel, P. Stringari, M. Suchenek, B. Sur, S. Tacchino, L. Takeuchi, M. Tardocchi, R. Tartaglia, E. Thomas, D. Trask, J. Tseng, L. Tseng, L. VanPagee, V. Vedia, B. Velghe, S. Viel, A. Visioli, L. Viviani, D. Vonica, M. Wada, D. Walter, H. Wang, M. Wang, S. Westerdale, D. Wood, D. Yates, S. Yue, V. Zambrano   +235 more
semanticscholar   +1 more source

Mechanical Ventilator Milano (MVM):A Novel Mechanical Ventilator Designed for Mass Scale Production in response to the COVID-19 Pandemics

medRxiv, 2020
We present here the design of the Mechanical Ventilator Milano (MVM), a novel mechan- ical ventilator designed for mass scale production in response to the COVID-19 pandemics, to compensate for the dramatic shortage of such ventilators in many countries.
Galbiati Cristiano, W. Bonivento, M. Caravati, M. Razeti, S. Dececco, G. Fiorillo, F. Gabriele, R. Tartaglia, A. Razeto, D. Sablone, E. Scapparone, G. Testera, M. Rescigno, D. Franco, I. Kochanek, C. Kendziora, S. Pordes, Hanguo Wang, A. Ianni, A. Mcdonald, L. Molinari Tosatti, T. Dinon, M. Malosio, D. Minuzzo, A. Zardoni, A. Prini   +25 more
semanticscholar   +1 more source

Response of a comprehensive cancer center to the COVID-19 pandemic: the experience of the Fondazione IRCCS–Istituto Nazionale dei Tumori di Milano

Tumori, 2020
Background: The rapid spread of coronavirus disease (COVID-19) is affecting many countries. While healthcare systems need to cope with the need to treat a large number of people with different degrees of respiratory failure, actions to preserve aliquots ...
F. Valenza, G. Papagni, Antonio Marchianò, M. Daidone, F. Debraud, M. Colombo, A. Frignani, G. Galmozzi, V. Ladisa, G. Pruneri, R. Salvioni, Pierangelo Spada, Michele Torresani, Oliviero Rinaldi, S. Manfredi, M. Votta, G. Apolone   +16 more
semanticscholar   +1 more source

Administration of apo A-I (Milano) nanoparticles reverses pathological remodelling, cardiac dysfunction, and heart failure in a murine model of HFpEF associated with hypertension

Scientific Reports, 2020
Therapeutic interventions with proven efficacy in heart failure with reduced ejection fraction (HFrEF) have been unsuccessful in heart failure with preserved ejection fraction (HFpEF).
Mudit Mishra, I. Muthuramu, H. Kempen, B. De Geest   +3 more
semanticscholar   +1 more source

Protective Effect of ApoA1 (Apolipoprotein A1)-Milano in a Rat Model of Large Vessel Occlusion Stroke

Stroke, 2020
Supplemental Digital Content is available in the text. Background and Purpose— Previous experimental studies found that the infusion of human purified nascent HDL (high-density lipoprotein) significantly reduced infarct volume and hemorrhagic ...
C. Ducroux, J. Désilles, M. Mawhin, S. Delbosc, B. Ho-Tin-Noé, V. Ollivier, L. Di Meglio, B. Lapergue, J. Michel, P. Amarenco   +9 more
semanticscholar   +1 more source

Effect of Infusion of High-Density Lipoprotein Mimetic Containing Recombinant Apolipoprotein A-I Milano on Coronary Disease in Patients With an Acute Coronary Syndrome in the MILANO-PILOT Trial: A Randomized Clinical Trial

JAMA cardiology, 2018
Importance Infusing a high-density lipoprotein mimetic containing apolipoprotein A-I Milano demonstrated potential atheroma regression in patients following an acute coronary syndrome.
S. Nicholls, R. Puri, C. Ballantyne, C. Ballantyne, J. Jukema, J. Kastelein, W. Koenig, W. Koenig, R. Wright, D. Kallend, P. Wijngaard, Marilyn Borgman, K. Wolski, S. Nissen   +13 more
semanticscholar   +1 more source

Fifteen Years of Airborne Particulates in Vitro Toxicology in Milano: Lessons and Perspectives Learned

International Journal of Molecular Sciences, 2020
Air pollution is one of the world’s leading environmental causes of death. The epidemiological relationship between outdoor air pollution and the onset of health diseases associated with death is now well established.
E. Longhin, P. Mantecca, M. Gualtieri
semanticscholar   +1 more source