Targeting brain, body and heart for cognitive health and dementia prevention [PDF]
This report looks into the current research regarding dementia and Alzheimer\u27s disease prevention and offers ideas for possible future solutions. Prevention of dementia is the ultimate aim of a large, albeit under resourced, international ...
Elodie O', Maree Farrow
core
Brain acetylcholinesterase activity in mild cognitive impairment and early Alzheimer's disease
J. O. Rinne
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Decreased EEG synchronization in Alzheimer’s disease and mild cognitive impairment [PDF]
Thomas Koenig+6 more
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Cholinergic Degeneration and Cognitive Function in Early GBA1‐Related Parkinson's Disease
Objective The phenotype of patients with Parkinson's disease carrying GBA1 variants (GBA‐PD) suggest similarities to symptomatology associated with early cholinergic system degeneration. Therefore, this study aims to investigate the clinical features and the cholinergic innervation pattern in patients with early GBA‐PD versus those without the GBA1 ...
Sofie Slingerland+6 more
wiley +1 more source
Cholinergic enhancement of frontal lobe activity in mild cognitive impairment [PDF]
Andrew J. Saykin+6 more
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Regional and Global Changes in Brain Structure 1‐Year Post Pediatric “Mild” Traumatic Brain Injury
Objective Despite the high prevalence of pediatric “mild” traumatic brain injury (pmTBI), very little is known about the long‐term effects of injury on brain structure and how injuries manifest in the context of dynamic and regionally specific neurodevelopmental changes. Methods Prospective study design characterizing long‐term effects of pmTBI on both
Upasana Nathaniel+15 more
wiley +1 more source
Autosomal Recessive Cerebellar Ataxias: Translating Genes to Therapies
Autosomal recessive cerebellar ataxias are disabling neurodegenerative genetic conditions affecting balance and coordination. Advancements in genomic testing have improved diagnosis, leading to a new focus on the development of targeted precision therapeutics addressing cellular, biochemical, and genetic disease mechanisms with a resulting emphasis on ...
Brent L. Fogel+10 more
wiley +1 more source
Neuropsychological features of mild cognitive impairment and preclinical Alzheimer's disease
Eva Arnáiz, Ove Almkvist
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Multiple Episodes of Mild Traumatic Brain Injury Result in Impaired Cognitive Performance in Mice [PDF]
Catherine E. Creeley+4 more
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Objective Although previous studies show that primary prophylaxis against Pneumocystis jirovecii pneumonia (PJP) is effective in patients with rheumatic diseases receiving immunosuppressive treatment, there is limited evidence regarding the optimal timing for prophylaxis withdrawal.
Ju Yeon Kim+5 more
wiley +1 more source