Results 181 to 190 of about 2,881,091 (302)

Mild cognitive impairment: why bother?

Annals of General Psychiatry, 2008
Gold Gabriel
doaj   +1 more source

Endothelial miR‐15a/16‐1 Regulation of SYNE1 Mediates Structural and Functional Recovery after Traumatic Brain Injury

Advanced Science, EarlyView.
Endothelial miR‐15a/16‐1 deletion promotes long‐term recovery after traumatic brain injury by restoring SYNE1 expression. Enhanced endothelial SYNE1 preserves vascular integrity, protects white and gray matter, and improves neurological function. The endothelial miR‐15a/16‐1–SYNE1 axis emerges as a key regulator of neurovascular repair and a potential ...
Shun Li, Na Qiu, Chao Zhou, Andrew Ni, Ping Sun, Jia‐Jun Liu, Xin‐Lei Huang, Tian‐Qing Xiong, Yu‐Chi Zhang, Hai‐Zhou Liu, Xiao‐Tao Xu, Rui Wang, Shi‐Qing Zhang, Yu‐Xin Zhang, Silvia Liu, C. Edward Dixon, Jun Chen, Ke‐Jie Yin   +17 more
wiley   +1 more source

Social cognition assessment in Chinese adults with mild cognitive impairment: a scoping review. [PDF]

Front Public Health
Liu Y, Zheng C, Cao J, Guo Q, Hu J, Lin Y, Pang Z, Song X, Zhai T, Dang F.   +9 more
europepmc   +1 more source

Mild cognitive impairment and subjective cognitive impairment [PDF]

Psychogeriatrics, 2008
Masatoshi TAKEDA, Takashi MORIHARA, Masayasu OKOCHI, Golam SADIK, Toshihisa TANAKA   +4 more
openaire   +1 more source

Dual‐Organelle Secretome Conjugation and Organ‐Uptake Tracking (DuO‐SCOUT) Enables Deep and Sensitive Mapping of the Secreted Proteins

Advanced Science, EarlyView.
A novel dual‐organelle proximity labeling platform, DuO‐SCOUT, decodes the complex landscape of systemic organ‐organ communication by capturing both classical and unconventional secretomes. Application in metabolic models maps the adipose‐to‐brain secretory relay, identifying selective extra‐hypothalamic sites for adipose‐derived factors and expanding ...
Fenglian Yang, Rui Qian, Jiaxing Song, Xingqi Meng, Jin Young Kim, Kwok On Lai, Li Wang, Liang Zhang   +7 more
wiley   +1 more source

Dietary (Poly)phenol Intake, Inflammatory Biomarkers, and Mild Cognitive Impairment in Italian Adults. [PDF]

Antioxidants (Basel)
Grasso M, L'Episcopo F, Toscano G, Frias-Toral E, Muratore S, Tripodi MA, Musso S, Bentivegna V, Costanzo L, Fatati G, Mascali C, Gullotta GS, Zambrano-Villacres R, León Brizuela L, Galvano F, Grosso G, Godos J, Ferri R, Lanza G, Caraci F.   +19 more
europepmc   +1 more source

Early Spatial and Contextual Coding Deficits in Hippocampal CA1 Precede Performance Decline in an Alzheimer's Disease Model

Advanced Science, EarlyView.
Two‐photon calcium imaging in behaving 5xFAD mice reveals early CA1 coding deficits before behavioral decline. Task‐related place cell activity and splitter cell trajectory coding are impaired, with reduced retrospective dominance and greater prospective weighting.
Yimei Li, Mary Ann Go, Hualong Zhang, Robertas Aleksynas, Juliana Kim, Mingyang Gao, Seigfred Prado, Magdalena Sastre, Simon R. Schultz   +8 more
wiley   +1 more source

TyG index and mild cognitive impairment and dementia: a review of current evidence. [PDF]

Front Aging Neurosci
Zhu Z, Xu J, Tang Z, Song N.
europepmc   +1 more source

14‐3‐3γ Protects Against Postoperative Cognitive Dysfunction by Regulating Tau Thr205 Phosphorylation and Synaptic Integrity

Advanced Science, EarlyView.
Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu, Xue Han, Heng Zhang, Chang Ye, Tianjiao Xia, Xiaoping Gu   +5 more
wiley   +1 more source

Hippocampal subfield diffusion abnormalities in Parkinson's disease with mild cognitive impairment: a volumetric and diffusion MRI study. [PDF]

Front Aging Neurosci
Chen Y, Peng L, Hu Q, Zhao Z, Xu B.
europepmc   +1 more source