Results 41 to 50 of about 8,065,301 (311)

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Mild solution of fractional order differential equations with not instantaneous impulses

open access: yes, 2015
In this paper, we investigate the boundary value problems of fractional order differential equations with not instantaneous impulse. By some fixed-point theorems, the existence results of mild solution are established.
Peiluan Li, Changjin Xu
semanticscholar   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Neutral functional differential equations of second-order with infinite delays

open access: yesElectronic Journal of Differential Equations, 2010
This work shows the existence of mild solutions to neutral functional differential equations of second-order with infinite delay. The Hausdorff measure of noncompactness and fixed point theorem are used, without assuming compactness on the associated
Runping Ye, Guowei Zhang
doaj  

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

Existence of the Mild Solution for Impulsive Semilinear Differential Equation

open access: yes, 2014
We study the existence of solutions of impulsive semilinear differential equation in a Banach space in which impulsive condition is not instantaneous. We establish the existence of a mild solution by using the Hausdorff measure of noncompactness and a ...
A. Chadha, D. Pandey
semanticscholar   +1 more source

Corrosion inhibition on mild steel in 1 M HCl solution by Cryptocarya nigra extracts and three of its constituents (alkaloids)

open access: yesRSC Advances, 2020
Corrosion inhibition effect of the crude extracts (hexane, dichloromethane, methanol) from the bark of Cryptocarya nigra and three alkaloids named N-methylisococlaurine 1, N-methyllaurotetanine 2 and atherosperminine 3 isolated from the Cryptocarya nigra
Mas Faiz   +3 more
semanticscholar   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Mild solution for fractional functional integro-differential equation with not instantaneous impulse

open access: yesMalaya Journal of Matematik, 2014
In this investigation, we prove the existence uniqueness and continuous dependence results of mild solution for nonlocal fractional differential equations with state dependent delay subject to not instantaneous impulse. We illustrate the existence result
Ganga Ram Gautam, Jaydev Dabas
semanticscholar   +1 more source

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