Results 61 to 70 of about 1,088,266 (333)
Nonautonomous Dynamical Systems, 2020 In this work, we present existence of mild solutions for partial integro-differential equations with state-dependent nonlocal local conditions. We assume that the linear part has a resolvent operator in the sense given by Grimmer.
Diop Mamadou Abdoul +3 more
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FEBS Letters, EarlyView.PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley +1 more source
AxiomsIn this paper, we investigate a fuzzy Hilfer fractional evolution equation of type ...
Kholoud N. Alharbi, Sanaa Alotaibi
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Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Existence of mild solutions for quasilinear integrodifferential equations with impulsive conditions
Electronic Journal of Differential Equations, 2009 We prove the existence and uniqueness of mild solutions of quasilinear integrodifferential equations with nonlocal and impulsive conditions in Banach spaces. The results are obtained by using a fixed point technique and semigroup theory. Examples are
Krishnan Balachandran +1 more
doaj
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
On a second-order evolution inclusion [PDF]
Results in Nonlinear Analysis, 2018 We study a class of second-order evolution inclusions and we obtain a sufficient condition for f-local controllability along a reference trajectory.
Aurelian Cernea
doaj
Boundary controllability of impulsive nonlinear fractional delay integro-differential system
Cogent Engineering, 2016 By using the strongly continuous semigroup theory and the Banach contraction principle, we study the boundary controllability of time varying delay impulsive nonlinear fractional integrodifferential system in Banach spaces.
Hamdy M. Ahmed
doaj +1 more source