Results 81 to 90 of about 474,133 (318)

Existence and Uniqueness of Mild Solution for Mixed type of Integro-Differential Equation [PDF]

مجلة التربية والعلم, 2018
In this paper, we study the existence and uniqueness of a mild solution of a nonlinear mixed Volterra – Fredholm integro-differential equation with nonlocal condition in Banach space. Furthermore, we study continuouce dependence of mild solution.
Akram H. Mahmood, Sara F. Abdullah
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Existence, Uniqueness and Stability of Mild Solution of Lipschitzian Quantum Stochastic Differential Equations [PDF]

, 2014
We introduce the concept of a mild solution of Lipschitzian quantum stochastic differential equations (QSDEs). Results on existence,uniqueness and stability of mild solution of QSDEs are established.
Agarana, M. C., Agboola, O.O., Oghonyon, G.J., Bishop, S.A., Anake, T. A.   +4 more
core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

EXISTENCE, UNIQUENESS AND STABILITY OF A MILD SOLUTION OF LIPSCHITZIAN QUANTUM STOCHASTIC DIFFERENTIAL EQUATIONS [PDF]

, 2015
We introduce the concept of a mild solution of Lipschitzian quantum stochastic differential equations (QSDEs). Results on the existence, uniqueness and stability of a mild solution of QSDEs are established.
Agarana, M. C., Agboola, O.O., Bishop, S.A., Oghonyon, J. G., Anake, T.A.   +4 more
core  

Controllability of Mild Solution to Hilfer Fuzzy Fractional Differential Inclusion with Infinite Continuous Delay

Fractal and Fractional
This work investigates the solvability of the generalized Hilfer fractional inclusion associated with the solution set of a controlled system of minty type–fuzzy mixed quasi-hemivariational inequality (FMQHI).
Aeshah Abdullah Muhammad Al-Dosari
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Existence, Uniqueness and stability of Mild Solution of Lipschitzian Quantum Stochastic Differential Equations [PDF]

, 2015
We introduce the concept of a mild solution of Lipschitzian quan-tum stochastic di_erential equations (QSDEs). Results on existence, uniqueness and stability of mild solution of QSDEs are established.
Agarana, M. C., Agboola, O.O., Bishop, S.A., Anake, T. A., Oghonyon, J. G.   +4 more
core  

Synsepalum dulcificum extract as green corrosion inhibitor for acid corrosion of mild steel in HCl solution [PDF]

Anticorrosive potential of Synsepalum dulcificum leaf extract on the corrosion of mild steel in HCl solution was investigated using chemical technique.
Abiola, Olusegun Kehinde, Kazeem, Wasiu Olasunkanmi   +1 more
core   +2 more sources