Regional coherence evaluation in mild cognitive impairment and Alzheimer's disease based on adaptively extracted magnetoencephalogram rhythms [PDF]
, 2011 This study assesses the connectivity alterations caused by Alzheimer's disease (AD) and mild cognitive impairment (MCI) in magnetoencephalogram (MEG) background activity.
Abasolo, Daniel +14 more
core +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Mild traumatic brain injury during infancy: Executive function and behavioural outcomes 24 months post-injury [PDF]
, 2014 Traumatic brain injury (TBI) is a leading cause of death and disability for children and young people worldwide. Research has found that children in infancy and early childhood are at the highest risk of sustaining a TBI; and that mild TBI accounts for a
Zareie, Setareh
core
MRI evidence for altered venous drainage and intracranial compliance in mild traumatic brain injury. [PDF]
, 2013 To compare venous drainage patterns and associated intracranial hydrodynamics between subjects who experienced mild traumatic brain injury (mTBI) and age- and gender-matched controls.
Straube, Andreas +22 more
core +2 more sources
FEBS Open Bio, EarlyView.Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
How to make mild (0.05%) chlorine solution [PDF]
Use mild (0.05%) chlorine solution to wash ungloved hands.Make new mild (0.05%) chlorine solution every day. Throw away any leftover solution from the day before.Publication date from document properties.chlorine-solution-liquid-mild.pdfchlorine-solution-
core
Versatile vector tools for efficient protein screening across multiple expression systems
FEBS Open Bio, EarlyView.A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source
Approximations of solutions to nonlinear Sobolev type evolution equations
Electronic Journal of Differential Equations, 2003 In the present work we study the approximations of solutions to a class of nonlinear Sobolev type evolution equations in a Hilbert space. These equations arise in the analysis of the partial neutral functional differential equations with unbounded delay.
Dhirendra Bahuguna, Reeta Shukla
doaj
Review of the risks and/or benefits of thyroxine treatment in ‘mild’ subclinical hypothyroidism [PDF]
, 2013 Subclinical hypothyroidism (SCH) is a form of mild thyroid failure and is a commonly encountered condition in clinical practice. It denotes the presence of a raised serum thyroid stimulating hormone (TSH) and normal serum free thyroid hormone ...
Agius, Rachel
core
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source