Results 91 to 100 of about 5,028,361 (312)

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Approximations of solutions to nonlinear Sobolev type evolution equations

open access: yesElectronic Journal of Differential Equations, 2003
In the present work we study the approximations of solutions to a class of nonlinear Sobolev type evolution equations in a Hilbert space. These equations arise in the analysis of the partial neutral functional differential equations with unbounded delay.
Dhirendra Bahuguna, Reeta Shukla
doaj  

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Existence results for mild solutions of impulsive periodic systems [PDF]

open access: yes, 2012
By applying the Horn's fixed point theorem, we prove the existence of \(T_0\)-periodic \(PC\)-mild solution of impulsive periodic systems when \(PC\)-mild solutions are ultimate ...
Yang, Y.   +3 more
core   +3 more sources

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

A Solution Method for Engineering Equilibrium Mathematics Modeling under Mild Conditions

open access: yes, 2011
In this paper, a solution for engineering equilibrium mathematics modeling (EEMM) is considered. To obtain a solution of EEMM, we present a new type alternating direction solution method, and then its convergence is also shown under mild conditions.
Guo Cheng Li
core   +1 more source

Remark on the uniqueness of the mild solution of SQG equation [PDF]

open access: yes, 2023
We study the two-dimensional surface quasi-geostrophic equation. Motivated by the uniqueness for the three-dimensional incompressible Navier-Stokes equations, we demonstrate that the uniqueness of the mild solution of the two-dimensional surface quasi ...
Iwabuchi, Tsukasa, Ueda, Ryoma
core  

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

open access: yesFEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda   +4 more
wiley   +1 more source

Corrosion inhibition of polyaniline for mild steel in hydrochloric acid solution

open access: yes, 2020
: Polyaniline (PANi) is one of the most widely studied conductive polymers. In this paper the corrosion inhibition behavior of PANi for mild steel in hydrochloric acid solution was investigated by weight loss measurement, potentiodynamic polarization ...
Xueqing Liu   +3 more
core  

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