Results 111 to 120 of about 4,403,877 (318)

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Initial-Boundary Value Problem with Dirichlet and Wentzell Conditions for a Mildly Quasilinear Biwave Equation

Учёные записки Казанского университета: Серия Физико-математические науки
For a nonstrictly hyperbolic mildly quasilinear biwave equation in the first quadrant, an initial-boundary value problem with the Cauchy conditions specified on the spatial half-line and the Dirichlet and Wentzell conditions applied on the time half-line
V. I. Korzyuk, J. V. Rudzko
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Approximation of optimal control for functional-differential equations by optimal control of equations without delay in infinite-dimensional spaces

Researches in Mathematics
The problem of optimal control for a functional-differential equation of parabolic type in a Banach space is studied. An approximation procedure is proposed, which consists of replacing the original equation by the system of parabolic equations without ...
O.V. Perehuda, O.A. Kapustian, V.V. Mogylova   +2 more
doaj   +1 more source

Approximation of solutions of the stochastic wave equation by using the Fourier series

Modern Stochastics: Theory and Applications, 2018
A one-dimensional stochastic wave equation driven by a general stochastic measure is studied in this paper. The Fourier series expansion of stochastic measures is considered.
Vadym Radchenko, Nelia Stefans’ka
doaj   +1 more source

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

Annals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold, Krzysztof W. Selmaj, Regina Berkovich, Jeffrey A. Cohen, Giancarlo Comi, Eva K. Havrdová, James K. Sheffield, Hetal Desai, Chun‐Yen Cheng, Jon V. Riolo, Andrew Thorpe, Erik DeBoer, Bruce A. C. Cree   +12 more
wiley   +1 more source

Almost Periodicity of Mild Solutions of Inhomogeneous Periodic Cauchy Problems

Journal of Differential Equations, 1999
The authors consider a mild solution \(u\) to the well-posed inhomogeneous Cauchy problem \[ u'(t)= A(t)u(t)+ f(t), \] on a Banach space \(X\), where \(A(\cdot)\) is periodic. For a problem on \(\mathbb{R}_+\) the authors show that \(u\) is asymptotically almost-periodic if \(f\) is asymptotically almost-periodic, \(u\) is bounded, uniformly continuous
Batty, C, Hutter, W, Rabiger, F
openaire   +3 more sources

Mesoporous ferrosilicates with high content of isolated iron species synthesized in mild buffer solution and their catalytic application

, 2008
The mesoporous ferrosilicates with high content of framework iron species have been synthesized under mild acidic conditions (pH 4.4, buffer solution) by co-condensation of iron acetylacetonate and a mixture of tetraethoxysilane (TEOS) and sodium ...
Liu, Jian, 杨启华, Jia, Guoqing, Feng, Zhaochi, Fan, Fengtao, Yang, Qihua, Li, Can, 李灿, Xin, Hongchuan   +8 more
core   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

Existence, Uniqueness and stability of Mild Solution of Lipschitzian Quantum Stochastic Differential Equations [PDF]

, 2015
We introduce the concept of a mild solution of Lipschitzian quan-tum stochastic di_erential equations (QSDEs). Results on existence, uniqueness and stability of mild solution of QSDEs are established.
Agarana, M. C., Agboola, O.O., Bishop, S.A., Anake, T. A., Oghonyon, J. G.   +4 more
core