Results 101 to 110 of about 1,107,444 (285)

Initial-Boundary Value Problem with Dirichlet and Wentzell Conditions for a Mildly Quasilinear Biwave Equation

Учёные записки Казанского университета: Серия Физико-математические науки
For a nonstrictly hyperbolic mildly quasilinear biwave equation in the first quadrant, an initial-boundary value problem with the Cauchy conditions specified on the spatial half-line and the Dirichlet and Wentzell conditions applied on the time half-line
V. I. Korzyuk, J. V. Rudzko
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Mild solutions for semilinear fractional differential equations

Electronic Journal of Differential Equations, 2009
The authors study the fractional semilinear differential equation with nonlocal conditions \[ D^{q}x(t)=-Ax(t)+f(t,x(t),Bx(t)),\qquad t\in [0,T], \] \[ x(0)+g(x)=x_0, \] where \(T>0 ...
Gisele M. Mophou, Gaston M. N'Guerekata
openaire   +2 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Global Mild Solutions of the Navier-Stokes Equations

, 2012
Here we establish a global well-posedness of \textit{mild} solutions to the three-dimensional incompressible Navier-Stokes equations if the initial data are in the space $\mathcal{X}^{-1}$ defined by $(1.3)$ and if the norms of the initial data in $\mathcal{X}^{-1}$ are bounded exactly by the viscosity coefficient $ $.
Lei, Zhen, Lin, Fang-hua
openaire   +2 more sources

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Weighted pseudo-almost periodic solutions for some neutral partial functional differential equations

Electronic Journal of Differential Equations, 2012
In this article we study the existence of weighted pseudo almost periodic solutions of an autonomous neutral functional differential equation with Stepanov-Weighted pseudo almost periodic terms in a Banach space.
Mondher Damak, Khalil Ezzinbi, Lotfi Souden   +2 more
doaj  

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source