Results 41 to 50 of about 48,836 (266)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Green Capsicum annuum Fruit Extract for Inhibition of Mild Steel Corrosion in Hydrochloric acid solution

International Journal of Electrochemical Science, 2012
We are reporting green capsicum annuum fruit extract as inhibitor for mild steel corrosion in acid solution. Inhibition potential of this aqueous fruit extract has been determined with the help of weight loss method and electrochemical techniques ...
Gopal Ji, Sudhish Kumar Shukla, Priyanka Dwivedi, Shanthi Sundaram, Eno E. Ebenso, Rajiv Prakash   +5 more
doaj   +1 more source

Microstructure and Properties of Press-Bonded Dissimilar Stainless Steel and Mild Carbon Steel Ingots

Metals, 2022
Dissimilar steel welds between stainless and mild steels are necessary for the efficient utilization of stainless steels in construction. In the present work, a dissimilar large-sized steel ingot was fabricated by press bonding a Q235 steel to a SUS 304 ...
Xuqiang Huang, Zhaoyang Lu
doaj   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

THERMODYNAMIC PROPERTIES AND CHARACTERIZATIONS OF CHITOSAN NANO-PARTICLES CORROSION INHIBITION ON THE SURFACE OF MILD STEELIN PEAT WATER MEDIA

Alchemy, 2016
The thermodynamic properties and characterizations of corrosion inhibition of chitosan nano-particles on the surface of mild steel in peat water media had been studied using weight loss method at temperatures of 30 - 50 oC.
Maria Erna, Emriadi Emriadi, Admin Alif, Syukri Arief   +3 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Comparative studies of two benzaldehyde thiosemicarbazone derivatives as corrosion inhibitors for mild steel in 1.0 M HCl

Results in Physics, 2018
Two benzaldehyde thiosemicarbazone derivatives namely 3-methoxy,4-hydroxyl-benzaldehyde thiosemicarbazone (MHBT) and 2-hydroxyl,3-methoxy-benzaldehyde thiosemicarbazone (HMBT) were synthesized and their inhibition behavior for mild steel in 1.0 M HCl ...
H.H. Zhang, Y. Chen, Z. Zhang
doaj   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Study of Stevia rebaudiana Leaves as Green Corrosion Inhibitor for Mild Steel in Sulphuric Acid by Electrochemical Techniques

International Journal of Electrochemical Science, 2012
The inhibition for the corrosion of mild steel in sulphuric acid solution by the extract of Stevia rebaudiana leaves has been studied using electrochemical impedance spectroscopy (EIS) and potentiodynamic polarization techniques.
Hui Cang, Wenyan Shi, Jinling Shao, Qi Xu   +3 more
doaj   +1 more source