Results 111 to 120 of about 282,295 (380)

Ferroptosis‐Mediated Hippocampal Neuronal Loss Post‐mTBI: Chromatin Accessibility Profiling and Single‐Nucleus Transcriptomics

Advanced Science, EarlyView.
Hippocampal single ‐nucleus transcriptomes and chromatin accessibility after mild traumatic brain injury reveal dentate granule neuron vulnerability driven by ferroptosis. The c‐Jun–Tmsb4x–Slc2a2 axis modulates lipid peroxidation and iron dysregulation.
Manrui Li, Qiuyun Yang, Shengqiu Qu, Yang Chen, Yang Shen, Yang Xu, Xilong Lin, Yihan Sun, Ying Chen, Meili Lv, Lin Zhang, Zengqiang Yuan, Weibo Liang, Xiameng Chen   +13 more
wiley   +1 more source

Characterizing the Risk of Depression Following Mild Traumatic Brain Injury: A Meta-Analysis of the Literature Comparing Chronic mTBI to Non-mTBI Populations

Frontiers in Neurology, 2020
Objective: Mild traumatic brain injury (mTBI) is associated with depressed mood acutely post-injury, but there is little evidence regarding long-term depression.
Sarah C. Hellewell, Caerwen S. Beaton, Thomas Welton, Stuart M. Grieve, Stuart M. Grieve, Stuart M. Grieve   +5 more
doaj   +1 more source

Disease Control and Prevention [PDF]

— i — Some thoughts about traumatic brain injury (TBI) data… …People are uneducated about traumatic brain injury. They don’t recognize it when it happens to them or their loved ones; they don’t know the extent of the public health problem….
Jean A. Langlois, Julie Louise Gerberding, Karen E. Thomas, Sc. D, Wesley Rutland-brown M. P. H   +4 more
core  

Association of Optical Coherence Tomography With Longitudinal Neurodegeneration in Veterans With Chronic Mild Traumatic Brain Injury

JAMA Network Open, 2020
Key Points Question Do veterans with a history of mild traumatic brain injury show greater neurodegeneration over time compared with control veterans with no history of head injury?
C. Gilmore, K. Lim, M. Garvin, Jui-Kai Wang, J. Ledolter, Alicia Fenske, Carolyn L. Gentz, Julie K. Nellis, Michael Armstrong, R. Kardon   +9 more
semanticscholar   +1 more source

Dipiperazine‐Phenyl Derivatives Based on Convergent Molecular Platforms Can Reverse Multidrug Resistance in Gram‐Negative Bacteria by Inhibiting Efflux and Permeabilizing Cell Membranes

Advanced Science, EarlyView.
By integrating a convergent molecular platform strategy, this study designed a novel dual‐target C5 to combat multidrug‐resistant Gram‐negative bacteria. C5 synergistically enhances antibiotic efficacy by inhibiting efflux pumps and increasing bacterial membrane permeability.
Jiale Dong, Ting Guo, Yi Huang, Yangchun Ma, Weijin Chen, Jie Xue, Jun Jiang, Enhui Dong, Yue Kong, Hang Ding, Wenlong Zhang, Shutao Ma   +11 more
wiley   +1 more source

Underlying Ehlers-Danlos syndrome discovered during neuro-ophthalmic evaluation of concussion patients: a case series

BMC Ophthalmology, 2019
Background The Ehlers-Danlos syndromes are a heterogenous group of diseases that cause connective tissue defects. At present, there are no published reports focusing upon the neuro-ophthalmic symptoms that might occur in EDS patients after mild traumatic
Abhishek Gami, Eric L. Singman
doaj   +1 more source

Sensory sensitivity as a link between concussive traumatic brain injury and PTSD. [PDF]

, 2019
Traumatic brain injury (TBI) is one of the most common injuries to military personnel, a population often exposed to stressful stimuli and emotional trauma.
Fanselow, Michael S, Giza, Christopher C, Hoffman, Ann N, Hovda, David A, Lam, Jamie   +4 more
core   +1 more source

Routine repeat head CT may not be necessary for patients with mild TBI. [PDF]

, 2018
Background:Routine repeat cranial CT (RHCT) is standard of care for CT-verified traumatic brain injury (TBI). Despite mixed evidence, those with mild TBI are subject to radiation and expense from serial CT scans.
Deane, Molly R, Luy, Diego D, Rosen, Claire B, Scalea, Thomas M, Stein, Deborah M   +4 more
core   +2 more sources

Organic Electrochemical Transistors in Tissue‐Interfaced Bioelectronics

Advanced Science, EarlyView.
This article reviews the design, fabrication, and biological application of organic electrochemical transistors (OECTs), emphasizing their potential in tissue‐interfaced bioelectronics. It covers the fundamental principles of OECTs, strategies for enhancing tissue interfacing, and the development of skin‐mounted and implantable systems.
Ruixiang Bai, Zeyu Zhao, Feng Yan
wiley   +1 more source

Satellite microglia: marker of traumatic brain injury and regulator of neuronal excitability

Journal of Neuroinflammation
Traumatic brain injury is a leading cause of chronic neurologic disability and a risk factor for development of neurodegenerative disease. However, little is known regarding the pathophysiology of human traumatic brain injury, especially in the window ...
Alicia B. Feichtenbiner, Karinn Sytsma, Ryan P. O’Boyle, Rhonda Mittenzwei, Heather Maioli, Kathryn P. Scherpelz, Daniel D. Child, Ning Li, Jeanelle Ariza Torres, Lisa Keene, Amanda Kirkland, Kimberly Howard, Caitlin Latimer, C. Dirk Keene, Christopher Ransom, Amber L. Nolan   +15 more
doaj   +1 more source