Results 121 to 130 of about 282,295 (380)

Vitamin therapy in the treatment of mild traumatic brain injury: new horizons of clinical practice

Український журнал військової медицини
Objective: To investigate the main aspects of the impact of vitamin therapy on the treatment effectiveness of patients with mild traumatic brain injury and to illustrate it on the example of individual clinical cases. Materials and Methods.
A. V. Shvets, K. V. Savichan, Ya. M. Klymenko   +2 more
doaj   +1 more source

Computational and in vitro studies of blast-induced blood-brain barrier disruption

, 2015
There is growing concern that blast-exposed individuals are at risk of developing neurological disorders later in life. Therefore, it is important to understand the dynamic properties of blast forces on brain cells, including the endothelial cells that ...
Banks, William A., Cook, David G., Del Razo, Mauricio J., Huber, B. Russell, Leveque, Randall J., Meabon, James S., Morofuji, Yoichi, Mourad, Pierre D., Peskind, Elaine R.   +8 more
core   +1 more source

Parental stress and burden following traumatic brain injury amongst children and adolescents [PDF]

, 2003
Primary objectives: to assess parental stress following paediatric traumatic brain injury (TBI) and examine the relationship between self-reported problems and parental stress and general health.
Hawley, Carol, Long, Julie, Magnay, Andrew R., Ward, Anthony B.   +3 more
core   +1 more source

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

Advanced Science, EarlyView.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu, Yunmin Zhu, Xi Wang, Zelin Wu, Zijian Xu, Rongqing Chen, Yanwu Guo   +6 more
wiley   +1 more source

Understanding practice: the factors that influence management of mild traumatic brain injury in the emergency department-a qualitative study using the Theoretical Domains Framework [PDF]

, 2014
Background: Mild traumatic brain injury is a frequent cause of presentation to emergency departments. Despite the availability of clinical practice guidelines in this area, there is variation in practice.
A Kuper, AM Patey, Australian Bureau of Statistics, B Heskestad, B Stuart, D Thurman, Denise A O’Connor, EJ Tavender, Emma J Tavender, F Servadei, ICEBeRG, IG Stiell, J Cane, J Kerr, J Kerr, J Ponsford, Jill J Francis, JJ Bazarian, JJ Francis, JJ Francis, Jonathan Knott, M Bosch, M Sandelowski, Marije Bosch, N Abelson-Mitchell, P Davies, R Baker, R Grol, R Grol, RD Vanderploeg, Russell L Gruen, S Buetow, S Faux, S Michie, S Michie, SA Berben, Sally E Green, SD French, SE Green, Susan Michie, T Bessen, T Ingebrigtsen, T Peachey, WH Ryu, WJ Meurer   +44 more
core   +2 more sources

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

Screening and outcomes of co-occurring traumatic brain injury among people with spinal cord injury: a scoping review

Journal of Rehabilitation Medicine
Objective: To map existing knowledge on screening and rehabilitation outcomes for co-occurring traumatic brain injury among people with traumatic spinal cord injury (SCI).
Deborah L. Snell, Phoebe Wynands, Jennifer Dunn, Joanne Nunnerley, Alice Theadom   +4 more
doaj   +1 more source

Outcomes following childhood head injury : a population study [PDF]

, 2004
Objectives: To identify outcomes following head injury (HI) amongst a population of children admitted to one hospital centre and compare outcomes between different severity groups. Methods:A postal follow-up of children admitted with HI to one NHS Trust,
Hawley, Carol, Long, Julie, Magnay, Andrew R., Ward, Anthony B.   +3 more
core   +2 more sources

Crossing the Blood–Brain Barrier with Molecularly Imprinted Polymeric Nanocarriers: An Emerging Frontier in Brain Disease Therapy

Advanced Science, EarlyView.
Molecularly imprinted polymeric nanocarriers (nanoMIPs) offer robust, antibody‐mimetic platforms to overcome the blood‐brain barrier. The article surveys nanoMIP design and ligand‐directed surface engineering that harness receptor‐mediated transcytosis, and highlights therapeutic and diagnostic applications in neurodegeneration, brain tumors and ...
Ranjit De, Shuliang Shi, Kyong‐Tai Kim
wiley   +1 more source

Examining and comparing the clinical characteristics of adults with persisting post-concussion symptoms presenting for outpatient rehabilitation following a mild traumatic brain injury or a minimal head injury

Journal of Rehabilitation Medicine
Objective: First, to describe a clinical sample with persisting post-concussion symptoms after a mild injury to the head. Second, to explore whether patients who sustained a mild traumatic brain injury differed from those with a minimal head injury (no ...
Linda Fordal, Grant L. Iverson, Julia E. Maietta, Alexander Olsen, Cathrine Einarsen, Simen B. Saksvik, Toril Skandsen   +6 more
doaj   +1 more source