Results 31 to 40 of about 2,000,835 (305)

Naming Commission Final Report: Part 2

open access: yes, 2022
Report summarizing the recommendations of The Naming Commission's findings regarding military academies in the United States as mandated by the National Defense Authorization Act for Fiscal Year 2021, which mandates the removal of names, symbols ...
United States. Naming Commission.
core  

Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis

open access: yesAdvanced Science, EarlyView.
Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang   +9 more
wiley   +1 more source

Phenotypes, Functions, and Clinical Relevance of Regulatory B Cells in Cancer

open access: yesFrontiers in Immunology, 2020
In immune system, B cells are classically positive modulators that regulate inflammation and immune responses. Regulatory B cells (Bregs) are a subset of B cells which play crucial roles in various conditions, including infection, allergies, autoimmune ...
Jin Shang, Haoran Zha, Yufa Sun
doaj   +1 more source

BAP31 Drives Cartilage Calcification through Disruption of Autophagosome–Lysosome Fusion in Osteoarthritis

open access: yesAdvanced Science, EarlyView.
Mechanical stress activates BAP31 in chondrocytes. BAP31 competes with ATG14 for binding to STX17, disrupting the STX17–ATG14 complex required for autophagosome–lysosome fusion. The resultant autophagic flux blockade drives the generation of autophagy‐derived exosomes, which mediate pathological cartilage calcification in OA. Chondrocyte‐targeted BAP31
Zhi‐hua Xu   +13 more
wiley   +1 more source

Komisja Centralna Likwidacyjna w Księstwie Warszawskim w latach 1808–1812

open access: yesKrakowskie Studia z Historii Państwa i Prawa, 2023
The Central Liquidation Commission in the Duchy of Warsaw between 1808 and 1812 The subject of the analysis concerns one of the administrative-legal aspects related to military requisitions in the ...
Marcin Konarski
doaj   +1 more source

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

open access: yesAdvanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo   +14 more
wiley   +1 more source

Mitochondrial SLC25A46 Rewires Fatty Acid Oxidation to Promote Cell Proliferation and Ferroptosis Evasion in Ovarian Cancer by Stabilizing CACT

open access: yesAdvanced Science, EarlyView.
Mitochondrial SLC25A46 is upregulated in ovarian cancer (OC) and correlates with poor prognosis. SLC25A46 stabilizes CACT to activate fatty acid oxidation, increasing ATP and NADPH production to drive cell proliferation and ferroptosis evasion. SLC25A46 silencing sensitizes OC cells to ferroptosis and carboplatin, offering a promising therapeutic ...
Yunge Gao   +9 more
wiley   +1 more source

BRASIL CRIA COMISSÃO DA VERDADE

open access: yesOxímora. Revista Internacional de Ética y Política, 2012
This study aimed to analyze the legal framework of the Truth Commission, an agency of the Department of Human Rights, in front of the Amnesty Act and as the Truth Commission can help to rescue omitted information during the Military Dictatorship, acting ...
Sérgio Tibiriçá   +1 more
doaj   +1 more source

Between Coups and Election: Constitutional Engineering and Military Entrenchment in Sudan

open access: yesAfrica Spectrum, 2022
This article investigates how armies re-entrench their power after thwarting democratic transitions. After the Sudanese military staged a coup in October 2021 and altered the transitional constitution, coup leader Abdelfattah al-Burhan announced the ...
Hager Ali   +2 more
doaj   +1 more source

BLACKSMITH’S HOUSE, “PAU DE ARARA”: THE REPRESSION WITHIN THE ARMY AND THE NARRATIVES OF THE DICTATORSHIP

open access: yesSemina, 2021
This article is based on a testimony collected by the National Truth Commission (CNV), in 2013, seeking to understand the discourse elaborated by the tortured, persecuted and purged soldiers of the Brazilian Army during the military ...
Bruno Almeida Silva
doaj   +1 more source

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