Results 51 to 60 of about 2,000,835 (305)
Advanced Science, EarlyView.PTEN knockdown activates AKT phosphorylation, promoting Nrf2 nuclear translocation and STAT3 activation, which upregulates GPX4 and antioxidant enzymes HO‐1, SOD1, SOD2, and NQO1. These coordinated changes reduce lipid peroxidation and ROS, inhibit ferroptosis, and ultimately ameliorate cognitive impairment in APP/PS1 transgenic mice, highlighting a ...
Da‐Wei Wang +5 more
wiley +1 more source
Advanced Science, EarlyView.LDHA‐driven lactate production in mesenchymal glioma stem cells promotes p300‐dependent H3K18 lactylation, activates USP30 transcription, and stabilizes MBOAT2 to remodel phosphatidylethanolamines toward ferroptosis‐resistant PE‐MUFA species. Disrupting this metabolic–epigenetic–lipid circuit enhances ferroptosis and sensitizes glioblastoma to ...
Zong Miao +13 more
wiley +1 more source
Cyberspace Solarium Commission
, 2020 Website of the Cyberspace Solarium Commission documenting the group's publications regarding cybersecurity strategy for the U.S.
United States. Cyberspace Solarium Commission
core
Advanced Science, EarlyView.Under normal conditions, MACF1 interacts with Rab14 and facilitates KIF16B‐mediated FGFR vesicle trafficking along microtubules to the plasma membrane, thereby supporting BMSC differentiation. In contrast, chronic GC exposure suppresses MACF1 expression, disrupting this transport and causing intracellular FGFR retention, which blunts osteogenic ...
Peihong Su +14 more
wiley +1 more source
Advanced Science, EarlyView.A multifunctional EV‐based nanoplatform (Ang‐TEVs@Gel) was engineered via preconditioning, surface targeting, and ROS‐responsive hydrogel encapsulation to reprogram microglia. This system restored autophagy via miR‐664a‐3p/PIK3CA axis, cleared myelin debris, resolved neuroinflammation, and promoted axon remyelination, ultimately achieving robust motor ...
Wu Xiong +17 more
wiley +1 more source
Investigaciones Geográficas, 2001 When the Mexico-US war ended, it was necessary to define the borderline between the two countries. The Guadalupe-Hidalgo (1848) and La Mesilla or Gadsden (1853) treaties specified these borders Each country assigned a commission that worked jointly and ...
Luz María O. Tamayo P. de Ham +1 more
doaj +1 more source
National Commission on Military, National, and Public Service: Interim Report Executive Summary
, 2019 Executive summary for the interim report of the National Commission on Military, National, and Public Service outlining their charge, findings from information-gathering, and areas for further research, with social media contacts for public ...
United States. National Commission on Military, National, and Public Service.
core
Advanced Science, EarlyView.Given that PEEK chest wall implants induce shear force at the soft tissue‐implant interface due to respiratory motion in the early in vivo post‐implantation stage. We confirmed that this mechanical stimulus triggers the PIEZO1/ITGB1/YAP1 signalling axis in L929 and the STAT6/p‐STAT6 pathway in RAW264.7, which in turn mediates adhesion and migration of ...
Rou Huang +14 more
wiley +1 more source
Revista Conjuntura Austral, 2016 This paper aims to analyze the impacts of the territorial expansion, during the military regime, in relation to Mato Grosso do Sul’s traditional societies located in the border region.
Marcio Augusto Scherma +1 more
doaj +1 more source
A Report to the American People, Congress, and the President
, 2019 Interim report of the National Commission on Military, National, and Public Service summarizing the information they gathered, ongoing research, and upcoming meetings regarding military selective service, as well as increasing military, national, and ...
United States. National Commission on Military, National, and Public Service.
core