Results 11 to 20 of about 555,665 (313)

Immune contexture defined by single cell technology for prognosis prediction and immunotherapy guidance in cancer

open access: yesCancer Communications, 2019
Tumor immune microenvironment is closely related to tumor initiation, prognosis, and response to immunotherapy. The immune landscapes, number of infiltrating immune cells, and the localization of lymphocytes in the tumor vary in across different types of
Tong Wu   +3 more
doaj   +1 more source

Between NATO and UN : EU strategic culture and its approach to civil-military cooperation [PDF]

open access: yes, 2018
The European Union's approach to civil-military cooperation (CIMIC) in crisis response incorporates two different perspectives. The EU’s official concept is shaped after NATO's military-centred vision and is subordinated to the achievement of military ...
Mazurkiewicz, Agata
core   +1 more source

Novel transketolase inhibitor oroxylin A suppresses the non‐oxidative pentose phosphate pathway and hepatocellular carcinoma tumour growth in mice and patient‐derived organoids

open access: yesClinical and Translational Medicine, 2022
Background Transketolase (TKT), a key rate‐limiting enzyme in the non‐oxidative branch of the pentose phosphate pathway (PPP), provides more than 85% of the ribose required for de novo nucleotide biosynthesis and promotes the development of ...
Dan Jia   +15 more
doaj   +1 more source

The Gut Microbiota, Tumorigenesis, and Liver Diseases

open access: yesEngineering, 2017
In recent decades, diseases concerning the gut microbiota have presented some of the most serious public health problems worldwide. The human host’s physiological status is influenced by the intestinal microbiome, thus integrating external factors, such ...
Guishuai Lv   +2 more
doaj   +1 more source

Why Japan could revise its constitution and what it would mean for Japanese security policy [PDF]

open access: yes, 2006
This article seeks to make sense of the policy debate on constitutional revision underway in Japan, to consider what international and domestic factors are driving the debate forward, to assess the range of proposals currently on the table, and to gauge ...
Hughes, Christopher W.
core   +1 more source

Military-Technical Cooperation of South-East Asian States with the United States and EU Countries (2011–2020)

open access: yesКонтуры глобальных трансформаций: политика, экономика, право, 2021
The article aims to identify the key trends and main areas of development of arms trade and military-technical cooperation between South-East Asian countries and the United States and European Union countries over the past decade (2011–2020). In addition
M. G. Yevtodyeva
doaj   +1 more source

F4/80+ Kupffer Cell-Derived Oncostatin M Sustains the Progression Phase of Liver Regeneration through Inhibition of TGF-β2 Pathway

open access: yesMolecules, 2021
The role of Kupffer cells (KCs) in liver regeneration is complicated and controversial. To investigate the distinct role of F4/80+ KCs at the different stages of the regeneration process, two-thirds partial hepatectomy (PHx) was performed in mice to ...
Qingjun Lu   +6 more
doaj   +1 more source

The Limits of U.S.-China Military Cooperation: Lessons from 1995-1999 [PDF]

open access: yes, 2005
"The Limits of U.S.-China Military Cooperation: Lessons from 1995-1999" (with Kurt Campbell) The Washington Quarterly 29: 1 (Winter 2005), pp.
Kurt Campbell, Richard Weitz
core   +1 more source

Sino-Russian military relations in People’s Daily in 2014-2022

open access: yesRUDN Journal of World History, 2023
The significance of the topic under study is due to substantial advancements in Sino-Russian military cooperation amid the 2014 Ukrainian crisis and Russia’s deteriorating relations with the West.
Anna S. Archugova   +1 more
doaj   +1 more source

Malignant progression of liver cancer progenitors requires lysine acetyltransferase 7–acetylated and cytoplasm‐translocated G protein GαS

open access: yesHepatology, EarlyView., 2022
KAT7‐acetylated and cytoplasm‐translocated G‐protein GαS enhances IL‐6 effect and drives HCC progenitor cell progression. Abstract Background and Aims Hepatocarcinogenesis goes through HCC progenitor cells (HcPCs) to fully established HCC, and the mechanisms driving the development of HcPCs are still largely unknown.
Ye Zhou   +15 more
wiley   +1 more source

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