Results 151 to 160 of about 101,903 (263)

A multiplex interactome of Ebola virus proteins reveals TM9SF2 as a cell‐surface attachment factor that promotes viral entry

open access: yesiMetaOmics, EarlyView.
This study generates a comprehensive Ebola virus (EBOV)‐human protein–protein interactome, comprising 1728 core high‐confidence interactions. Further interactome analysis revealed the potential association of EBOV glycoprotein (GP) with the host factor TM9SF2. Subsequent mechanistic investigations confirmed that TM9SF2 functions as an attachment factor
Limin Shang   +16 more
wiley   +1 more source

Microbiome and aging: Trajectories of microbiome age across human ecosystems and their systemic effects

open access: yesiMeta, EarlyView.
Microbiome age (MA) has emerged as an innovative biomarker of biological aging, reflecting host aging trajectories through dynamic alterations in microbial composition, function, and host–microbe interactions across multiple body ecosystems. Diverse computational strategies—including traditional machine learning, deep learning, and multi‐omics ...
Zhexin Ni   +26 more
wiley   +1 more source

Microbial metabolite indole‐3‐propionic acid preserves astrocytic mitochondrial mitofusin 2 to limit neuroinflammation after traumatic brain injury

open access: yesInterdisciplinary Medicine, EarlyView.
Following traumatic brain injury, indole‐3‐propionic acid (IPA) directly targets the aryl hydrocarbon receptor on astrocytes in the peri‐lesional cortex; this suppresses interferon regulatory factor 1‐driven transcription of the E3 ubiquitin ligase RFFL (ring finger and FYVE‐like domain containing E3 ubiquitin protein ligase).
Ziwen Zhang   +22 more
wiley   +1 more source

Noise exposure burden and hearing protection compliance among Saudi military personnel: A cross-sectional study. [PDF]

open access: yesS Afr J Commun Disord
Alanazi AA   +4 more
europepmc   +1 more source

Monuments to Injustice and the Ethics of Dark Tourism: A Research Note

open access: yesJournal of Applied Philosophy, EarlyView.
ABSTRACT This research note aims to motivate philosophical examination of the ethical tensions surrounding ‘dark tourism’ and monuments to injustice. While such monuments function to acknowledge past wrongs, educate the public, and serve reparative functions, their presentation as tourist destinations can undermine these purposes.
Kok‐Chor Tan
wiley   +1 more source

AI-enabled proactive health education: perceptions of public health students - a qualitative study. [PDF]

open access: yesBMC Med Educ
Wang J   +8 more
europepmc   +1 more source

Differential Associations Between Relational Health and Mental Health Among Civilian and Military‐Affiliated Samples Reporting Moral Injury

open access: yesJournal of Counseling &Development, EarlyView.
ABSTRACT The symptoms of anxiety and depression are commonly reported within military‐ and non‐military‐affiliated populations, with considerable evidence available to counselors regarding which relational characteristics function as protective factors among these populations.
A. Stephen Lenz   +2 more
wiley   +1 more source

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