Results 41 to 50 of about 101,903 (263)

IKKβ and USP28 Regulate HEY1 Stability to Promote Cancer Stemness and Immune Evasion in Hepatocellular Carcinoma

Advanced Science, EarlyView.
The uncovered IKKβ‐USP28‐HEY1 axis fuels cancer stemness and immune evasion in hepatocellular carcinoma. USP28 deubiquitinates HEY1 upon IKKβ‐mediated phosphorylation, conferring PD‐1/PD‐L1 blockade resistance. Pharmacological inhibition of USP28 sensitizes resistant tumors to anti‐PD‐1 immunotherapy, revealing a promising therapeutic strategy ...
Na Shao, Lin Zhang, Gufang Shen, Yangfan Lv, Tianshu Fang, Ya Cao, Qiongyi Zhang, Feng Xu, Chungang Liu   +8 more
wiley   +1 more source

LEADERSHIP COMPETENCE OF SIGNAL AND CYBERSECURITY OFFICERS: ESSENCE, STRUCTURE, AND CONTENT

Збірник наукових праць Національної академії Державної прикордонної служби України. Серія: педагогічні науки
This article presents a comprehensive analysis of the theoretical foundations underpinning the formation and development of leadership competence to officers of the signal and cybersecurity forces in the face of modern military challenges.
Mykhailo PASKO
doaj   +1 more source

DIVERGENT OR CONVERGENT TRENDS IN PROFESSIONAL MILITARY EDUCATION IN SLOVENIA? [PDF]

Journal of Defense Resources Management, 2017
There is a decade long discussion about the professional military education in Slovenia. The country has developed its own military force after the independence in 1991.
Maja Garb
doaj  

Democracy and education: Notes over military training in Argentina and Brazil

Íconos, 2020
This article assumes that the countless military interventions and coups, and the decades in which both Argentina and Brazil lived under dictatorships; constitute an obstacle for democracy and reveal the importance of educating soldiers on the importance
Ana Penido, Suzeley Kalil Mathias, Eduardo Mei.   +2 more
doaj   +1 more source

Study of Educational Adjustment and Educational Motivation in Military and Non-Military Students

Journal of Social Sciences, 2008
Students abilities to transfer from the community colleges into baccalaureate granting colleges and universities have become a global issue. The rise in students’ college attendance has brought about new challenges in the area of academic motivation depriving them from educational pursuit despite proper qualifications.
Khodabakhsh Ahmadi, Ali Fathi-Asht
openaire   +1 more source

A Sprayable Nanoplatform Breaks the Vicious Cycle of Diabetic Wounds via Photoactivated Antioxidant and Drug Delivery

Advanced Science, EarlyView.
A sprayable near‐infrared‐activated nanoplatform incorporating MXene, ZnHCF nanozyme, and deferoxamine efficiently breaks the vicious cycle of diabetic wounds. Upon irradiation, interfacial electron transfer and photothermal effects enhance multi‐enzyme activity, enabling explosive ROS elimination, alleviation of hypoxia, and controlled DFO release ...
Jiahao Guo, Yuanyuan Meng, Qixiang Gui, Xi‐Tao Yang, Yong Fan, Xiaodong Zhu   +5 more
wiley   +1 more source

Supercritical CO2‐Induced Porous MXene Films for Electromagnetic Interference Shielding and Infrared Stealth

Advanced Science, EarlyView.
The phase transition of supercritical CO2 induces the foaming of dense MXene film without compromise inherent structure of MXene nanosheet. The foamed porous MXene film manifests remarkable EMI shielding and infrared thermal camouflage performances. Moreover, the foaming strategy is broadly adaptable and can be extended to other two‐dimensional films ...
Hui Zhao, Shuai Li, Jiabei He, Tong Gao, Jingfeng Wang, Dongxiao Kan, Wangtu Huo, Lixin Chen   +7 more
wiley   +1 more source

Cholesterol‐Mediated Metabolic‐mechanotransductive Crosstalk Orchestrates Castration Resistance in Prostate Cancer

Advanced Science, EarlyView.
Full androgen deprivation (FAD) induces paracrine cholesterol in prostate cancer that drives the polarization of cancer‐associated fibroblasts (CAFs) and subsequent elevated matrix stiffness. Matrix stiffness in turn potentiates tumor cell survival under FAD pressure via dual mechanotransductive activation of the IRE1α‐XBP1s stress‐response axis ...
Shaojie Liu, Chao Xu, Jun Jiang, Limin He, Yike Zhou, Zhengxuan Li, Yu Li, Keying Zhang, Fa Yang, Tong Lu, Hongtao Song, Hai Zhu, Zhihao Hu, Xiaolong Zhao, Kai Gan, Hongji Li, Bo Yang, Rui Zhang, Weihong Wen, Donghui Han, Weijun Qin   +20 more
wiley   +1 more source

Ethnoconfessional Policy Towards Poles in the Military School of the Russian Empire (1830s – 1860s)

Журнал Фронтирных Исследований
The relevance of the topic of this study is caused by the necessity of identifying the causes of negative attitudes of Poles towards Russia and of eliminating the false stereotypes in the interpretation of imperial policy towards Catholics in general ...
Alexey N. Grebenkin
doaj   +1 more source

Designer Dynamic DNA Nanoaggregate in Living Cell for Mitochondrial Energy Restriction

Advanced Science, EarlyView.
This study presents the Tech‐tetrahedron, a designer dynamic DNA nanoaggregate engineered for precise mitochondrial energy restriction. Its trinity‐functionalized design integrates navigable unit, telomerase‐activated latch, and self‐assembly module.
Ruijia Deng, Jing Sheng, Ben Niu, Wenjuan Fu, Yingjie Yang, Zuowei Xie, Shuang Xie, Yunxuan He, Meilin Gong, Jue Wang, Yan Pi, Ming Chen, Kai Chang   +12 more
wiley   +1 more source