Results 51 to 60 of about 100,959 (263)

Microglia‐Targeted Biomimetic Tetrahedral Framework Nucleic Acid Nanovesicles for Synergistic Treatment of Sepsis‐Associated Encephalopathy

open access: yesAdvanced Science, EarlyView.
Sepsis‐associated encephalopathy (SAE) lacks effective therapies. We developed ME@FDsi, a biomimetic nanodrug using a tetrahedral framework nucleic acid to deliver disulfiram and siTNFα. It crosses the blood‐brain barrier, targets M1 microglia, inhibits pyroptosis and inflammation, and scavenges ROS.
Huimin Shi   +15 more
wiley   +1 more source

BEST PRACTICE PRINCIPLES FOR PROFESSIONAL MILITARY EDUCATION: A LITERATURE REVIEW [PDF]

open access: yesJournal of Defense Resources Management, 2019
This paper reviews the best practice principles that support the tertiary level military education programmes, as highlighted in the existing literature.
Claire GOODE
doaj  

Advances and Perspectives in Graphene‐Based Quantum Dots Enabled Neuromorphic Devices

open access: yesAdvanced Science, EarlyView.
Graphene‐based QDs are zero‐dimensional carbon nanomaterials with pronounced quantum confinement and tunable electronic structures. Herein, we summarize their synthesis strategies and functionalization methods, and highlight their functional roles and operating mechanisms in devices, as well as recent advances in neuromorphic electronics. We anticipate
Yulin Zhen   +9 more
wiley   +1 more source

MILITARY EDUCATION AT A NON-MILITARY UNIVERSITY: THE ROAD TO STABILITY

open access: yesВысшее образование в России, 2016
The article reviews military education formation and development in a non-military university by the example of Voronezh State University. It analyzes the educational activity and specialist training quality provided by the Military Training Centre over ...
Dmitry A. Endovitsky, Viktor G. Shamaev
doaj  

Lost in Transition: The Dissemination of Digitization and the Challenges of Leading in the Military Educational Organization

open access: yesFrontiers in Psychology, 2019
Leading change in adult educational organizations is not frequently described in the leadership literature. The education sector in the Norwegian Armed Forces (NAF) is in the middle of an educational reform that requires major changes.
Torill Holth, Ole Boe
doaj   +1 more source

Zero Thermal Expansion and Local Structure in KxMnxFe2‐xMo3O12‐Based Materials

open access: yesAdvanced Science, EarlyView.
Local structure engineering via ion insertion drives local structural transformation from low‐symmetry P21/a to high‐symmetry R‐3c, enhancing structural flexibility and realizing a transition from positive thermal expansion to wide‐temperature‐range zero thermal expansion in KxMnxFe2‐xMo3O12‐based materials.
Gongsen He   +13 more
wiley   +1 more source

Escuela, cuerpo y milicia, historias de un redoble, de un simulacro que no termina Escola, corpo e milícia, histórias de um rumor, de um simulacro que não termina School, body and militia, stories of a frill; a simulation that doesn't stop

open access: yesEducar em Revista, 2009
El artículo presenta un análisis de los intercambios sensibles que se proyectan, con relación a las prácticas educativas corporales, desde los discursos de apropiación e intervención para la conformación de niños y jóvenes escolarizados de Medellín en la
William Moreno Gómez
doaj   +1 more source

Pathogen‐Centric Activation of an Azoreductase‐Responsive Antibody‐Antibiotic Conjugate for the Targeted Eradication of MRSA

open access: yesAdvanced Science, EarlyView.
A pathogen‐centric antibody‐antibiotic conjugate (AZO‐AAC) releases antibiotics via bacterial azoreductase, independent of host‐lysosomal function. This mechanism achieves nanomolar eradication of both planktonic and intracellular methicillin‐resistant Staphylococcus aureus (MRSA).
Qi Cheng   +13 more
wiley   +1 more source

BCMA‐Engineered Dendritic Cell‐Derived Exosomes as Bi‐Functional Therapeutics Orchestrating Cytokine Sequestration and Immune Activation for Multiple Myeloma

open access: yesAdvanced Science, EarlyView.
A dual‐function cell‐free therapeutic based on DC2.4 cell‐derived exosomes engineered to display BCMA. (Left) Soluble Ligand Sequestration (Decoy Function): DB Exo act as molecular decoys that predominantly sequester soluble APRIL with partial BAFF attenuation, effectively disrupting the NF‐κB survival signaling axis and suppressing myeloma cell ...
Yuqing Zeng   +5 more
wiley   +1 more source

THE IMAGE OF THE PROFESSIONAL FUTURE AND SPORT ENGAGEMENT OF THE CADETS OF THE INSTITUTE OF THE NATIONAL GUARD TROOPS OF THE RUSSIAN FEDERATION

open access: yesВестник Кемеровского государственного университета, 2018
The research defines the relationship between the content of the image of the professional future and sport engagement in the future N ational Guardsmen. Methods: the study involved 170 cadets of the military institute.
A. V. Kuznetsov, A. A. Utyuganov
doaj   +1 more source

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