Results 81 to 90 of about 5,419,240 (313)

Metabolic Reprogramming in Glioblastoma Stem Cells Promotes Radiation Resistance Through a H3K18la/USP30/MBOAT2 Axis

open access: yesAdvanced Science, EarlyView.
LDHA‐driven lactate production in mesenchymal glioma stem cells promotes p300‐dependent H3K18 lactylation, activates USP30 transcription, and stabilizes MBOAT2 to remodel phosphatidylethanolamines toward ferroptosis‐resistant PE‐MUFA species. Disrupting this metabolic–epigenetic–lipid circuit enhances ferroptosis and sensitizes glioblastoma to ...
Zong Miao   +13 more
wiley   +1 more source

TECHNOLOGICAL CONTRIBUTIONS OF THE MILITARY ENGINEERING TO THE NATIONAL DEVELOPMENT

open access: yesPolítica y Estrategia, 2018
The development of the Chilean military industry is closely related to the growing of the national industry. Similarly to the way the history of the Army and the country are tightly related, the history of the military engineering is an example of ...
RODRIGO CARO DE KARTZOW
doaj   +1 more source

Regulations of the Virginia Military Institute, 1931

open access: yes, 1931
Regulations for the Corps of Cadets of the Virginia Military Institute. These regulations governed all aspects of cadet life.
Virginia Military Institute
core  

Dysregulation of the MACF1‐Rab14/KIF16B‐FGFR Vesicular Trafficking Axis Skews MSC Lineage Commitment in Glucocorticoid‐Induced Osteoporosis

open access: yesAdvanced Science, EarlyView.
Under normal conditions, MACF1 interacts with Rab14 and facilitates KIF16B‐mediated FGFR vesicle trafficking along microtubules to the plasma membrane, thereby supporting BMSC differentiation. In contrast, chronic GC exposure suppresses MACF1 expression, disrupting this transport and causing intracellular FGFR retention, which blunts osteogenic ...
Peihong Su   +14 more
wiley   +1 more source

Regulations of the Virginia Military Institute, 1923

open access: yes, 1923
Regulations for the Corps of Cadets of the Virginia Military Institute. These regulations governed all aspects of cadet life.
Virginia Military Institute
core  

Sticker Valence Governs Chain Collapse and Liquid‐Liquid Phase Separation in Peptide‐Inspired Associative Polymers

open access: yesAdvanced Science, EarlyView.
Peptide‐inspired associative polymers with arginine‐like guanidinium stickers and lysine‐like ammonium spacers undergo chain collapse and liquid‐liquid phase separation induced by reversible sticker associations. Sticker valence and tunable association strength jointly control the phase behavior, chain conformation, and interfacial cohesion of these ...
Seung‐Hwan Oh   +7 more
wiley   +1 more source

James Tubbs Interview

open access: yes, 2005
Col. James O. Tubbs commissioned in the USAF in 1980 and since that date has served as a Standardization and Evaluation Pilot at the 23rd Tactical Air Support Squadron, Shaw AFB, SC (1983 – 1986); Flight Commander and Instructor Pilot, 496th Tactical ...
Tubbs, James O.
core  

A Multidimensional Engineering Strategy Reprograms Microglia via Targeted and Sustained‐Release Extracellular Vesicles for Spinal Cord Injury Repair

open access: yesAdvanced Science, EarlyView.
A multifunctional EV‐based nanoplatform (Ang‐TEVs@Gel) was engineered via preconditioning, surface targeting, and ROS‐responsive hydrogel encapsulation to reprogram microglia. This system restored autophagy via miR‐664a‐3p/PIK3CA axis, cleared myelin debris, resolved neuroinflammation, and promoted axon remyelination, ultimately achieving robust motor ...
Wu Xiong   +17 more
wiley   +1 more source

General J. H. Binford Peay III Interview

open access: yes, 2007
Following his distinguished career in the U. S. Army, General J. H. Binford Peay III became VMI's 14th Superintendent in 2003. The first interview covers his years as a VMI cadet, from 1958-1962; the second contains reflections on his military service ...
Peay, J. H. Binford III;
core  

Alternating Shear Force of Respiration Regulates Cell Interactions of Fibroblasts and Macrophages to Promote Soft Tissue Integration of Chest Wall Polyetheretherketone Implants

open access: yesAdvanced Science, EarlyView.
Given that PEEK chest wall implants induce shear force at the soft tissue‐implant interface due to respiratory motion in the early in vivo post‐implantation stage. We confirmed that this mechanical stimulus triggers the PIEZO1/ITGB1/YAP1 signalling axis in L929 and the STAT6/p‐STAT6 pathway in RAW264.7, which in turn mediates adhesion and migration of ...
Rou Huang   +14 more
wiley   +1 more source

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