Results 151 to 160 of about 163,915 (302)

Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy

open access: yesHepatology, EarlyView., 2022
Abstract Background and Aims Current liver‐directed gene therapies look for adeno‐associated virus (AAV) vectors with improved efficacy. With this background, capsid engineering is explored. Whereas shuffled capsid library screenings have resulted in potent liver targeting variants with one first vector in human clinical trials, modifying natural ...
Nadja Meumann   +25 more
wiley   +1 more source

Establishment and evaluation of a novel rat model of the fourth ventricle hemorrhage

open access: yesAnimal Models and Experimental Medicine, EarlyView.
In this study, a novel rat model of fourth ventricle hemorrhage was established via autologous blood injection through the foramen of Magendie. Anesthetized rats were positioned in a stereotaxic apparatus with their heads tilted downward at an angle of approximately 20° relative to the vertical axis.
Chuhua Fu   +8 more
wiley   +1 more source

AIF1+CSF1R+ MSCs, induced by TNF‐α, act to generate an inflammatory microenvironment and promote hepatocarcinogenesis

open access: yesHepatology, EarlyView., 2022
Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong   +9 more
wiley   +1 more source

Military emergency medicine [PDF]

open access: bronze, 2004
Eric McDonald
openalex   +1 more source

Characterization of Neuropsychiatric Conditions in United States Resettled Refugees at a Single Academic Center

open access: yesAnnals of Neurology, EarlyView.
Neuropsychiatric diseases are common among forcibly displaced persons, and a better understanding is needed to improve screening and treatment efforts. We performed a retrospective cross‐sectional study at a single academic center looking at neuropsychiatric diagnoses of United States resettled refugees presenting for their domestic medical examination.
Noor F. Shaik   +2 more
wiley   +1 more source

Medical Studentsʼ Attitudes toward Military Medicine

open access: bronze, 2000
Joan P. Liman, Kenneth G. Swan
openalex   +1 more source

Towards Polymer Composite‐Based Transient Electronic Systems

open access: yesAdvanced NanoBiomed Research, EarlyView.
Biodegradable electronic systems are gaining attention for implantable biomedical applications, targeting disease treatment and lifespan extension. This review covers advances in biocompatible, biodegradable polymer composites using synthetic and natural polymers with conductive, semiconductive, and insulating fillers.
Gwan‐Jin Ko   +5 more
wiley   +1 more source

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