Results 101 to 110 of about 776,021 (358)

NNMT Orchestrates Metabolic‐Epigenetic Reprogramming to Drive Macrophage‐Myofibroblast Transition in Hypertrophic Scarring

open access: yesAdvanced Science, EarlyView.
In macrophage‐myofibroblast transition, upregulated NNMT depletes S‐Adenosylmethionine‌ (SAM) and nicotinamide adenine dinucleotide(NAD+), thereby triggering epigenetic reprogramming via Histone H3 Lysine 27 acetylation (H3K27ac) accumulation at the promoter region of master transcription factor Prrx1.
Xiwen Dong   +11 more
wiley   +1 more source

«HYBRID WAR» OF NOTIONS

open access: yesVestnik MGIMO-Universiteta, 2016
Ofer Fridman holds the degrees of BA (Military History and Security Studies) from Hebrew University, MA (Counter-Terror and Homeland Security) from Interdisciplinary Center Herzliya and PhD (Political Science, supervised by Prof.
O. Fridman
doaj   +1 more source

STRATEGI PEMBERDAYAAN GURU MILITER PADA LEMBAGA PENDIDIKAN JAJARAN KODIKLAT TNI AD DI WILAYAH CIMAHI [PDF]

open access: yes, 2016
Strategi pemberdayaan guru militer (Gumil) merupakan suatu hal yang sangat penting dan harus mendapat perhatian serius dari pihak Administrasi Pendidikan.
Padmawati, Hety
core  

Expandable Nanocomposite Shape‐Memory Hemostat for the Treatment of Noncompressible Hemorrhage

open access: yesAdvanced Science, EarlyView.
A nanocomposite‐coated shape memory foam rapidly expands, accelerates clotting, and reduces blood loss in vivo. Its fast volumetric expansion and strong procoagulant activity make it a promising hemostat for treating deep, noncompressible hemorrhage.
Saptarshi Biswas   +12 more
wiley   +1 more source

Engineering data compendium. Human perception and performance. User's guide [PDF]

open access: yes
The concept underlying the Engineering Data Compendium was the product of a research and development program (Integrated Perceptual Information for Designers project) aimed at facilitating the application of basic research findings in human performance ...
Boff, Kenneth R., Lincoln, Janet E.
core   +1 more source

CHB‐Induced Immune Zonation Chaos Elicited LXRα‐mediated Lipid Metabolism Disorders in Kupffer Cells to Induce Cancer Stem Cell Formation

open access: yesAdvanced Science, EarlyView.
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi   +18 more
wiley   +1 more source

All-pay war [PDF]

open access: yes
We study a model of war in which the outcome is uncertain not because of luck on the battlefield (as in standard models), but because the involved countries lack information about their opponent.
Hadi Yektas, Roland Hodler
core  

Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium

open access: yesAdvanced Science, EarlyView.
This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du   +5 more
wiley   +1 more source

Do Advanced Spatial Strategies Depend on the Number of Flight Hours? The Case of Military Pilots [PDF]

open access: gold, 2021
Marco Giancola   +7 more
openalex   +1 more source

TriCON: A Carbon‐Based Triple‐Modal Nanoplatform for Pancreatic Cancer Therapy

open access: yesAdvanced Science, EarlyView.
We developed TriCON, a triple‐modality nanotherapeutic platform, to treat pancreatic ductal adenocarcinoma (PDAC) by synergizing gene editing, chemotherapy, and immunotherapy. TriCON utilizes CRISPR/Cas9 to target the poliovirus receptor (PVR), combined with nano‐encapsulated doxorubicin and checkpoint blockade. This approach achieved significant tumor
Xinyu Peng   +9 more
wiley   +1 more source

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