Results 101 to 110 of about 8,449,269 (337)

Epigenetic Silencing of RFX7 Defines a Transcriptional Axis Linking Lactate Metabolism to Immune Checkpoint Therapy in Glioblastoma

Advanced Science, EarlyView.
Glioblastoma (GBM) exhibits RFX7 silencing via promoter hypermethylation, which downregulates PIK3IP1 to activate PI3K/AKT signaling, increase lactate accumulation, and enhance histone H4K12 lactylation. This lactylation upregulates PD‐L1/CSF1 expression and drives the immunosuppressive microenvironment formation.
Liying Han, Jinpeng Zhou, Gang Zhu, Fan Chen, Leiyang Li, Wenxing Cui, Fang Sun, Tian Feng, Yue Zhang, Qiang Wang, Shuoyao Ma, Chengxuan Guo, Ziwen Zhang, Kai Wang, Jiahui Wang, Liangbo Wang, Wencong Li, Chenyi Yuan, Haixiao Liu, Liang Wang, Yan Qu   +20 more
wiley   +1 more source

Intelligentization of warfare: Сhina's application of artificial intelligence in the military sphere and its geopolitical implications

Китаєзнавчі дослідження
The article studies how China is using and developing artificial intelligence (AI) for its army. This is a big part of China’s plan to modernize and make its military smarter.
Stanislav Shumlianskyi, Igor Svietlichnyi   +1 more
doaj   +1 more source

Advances and Perspectives in Graphene‐Based Quantum Dots Enabled Neuromorphic Devices

Advanced Science, EarlyView.
Graphene‐based QDs are zero‐dimensional carbon nanomaterials with pronounced quantum confinement and tunable electronic structures. Herein, we summarize their synthesis strategies and functionalization methods, and highlight their functional roles and operating mechanisms in devices, as well as recent advances in neuromorphic electronics. We anticipate
Yulin Zhen, Wei Zeng, Zherui Zhao, JiYu Zhao, Ziyan Huang, Zhuo Chen, Kui Zhou, Guanglong Ding, Su‐Ting Han, Ye Zhou   +9 more
wiley   +1 more source

The strategy of Ukrainian - U.S. defense and military relations on the modern stage [PDF]

, 2003
This thesis analyses the strategy of modern Ukrainian - U.S. defense and military relations in three areas: Defense Relations; Military Relations; and Civil-Military Relations.
Verbytskyi, Serhii
core  

Strategic Interdependence: Using Internet Outage Data to Study How Combatants Manage Collective Institutions During War

British Journal of Political Science
This article challenges the view that war and interdependence are inherently incompatible by examining how combatants manage collective institutions during conflict.
Nadiya Kostyuk, Jon Lindsay, Eunji Emily Kim, Aniket Anand, Zachary Bischof, Amanda Meng, Alberto Dainotti   +6 more
doaj   +1 more source

THE IMPACT OF SCIENCE AND TECHNOLOGY ON MILITARY STRATEGY [PDF]

Annals: Series on Military Sciences, 2012
In this article, some opinions regarding the between military sciences (and also technologies) and the military strategy are briefly presented. There are credible arguments that the modem and reliable technologies nave been a catalyst and a driving ...
Ion Alexandru PLĂVICIOSU, Eugen SITEANU   +1 more
doaj  

Electrostatic Self‐Assembly Induced Nest‐Like MXene Networks on Fabric for Ultra‐Broadband Flexible Absorption

Advanced Science, EarlyView.
In this study, an electrostatically self‐assembled WPU‐MXene@FC flexible fabric constructs a “nest‐like” structure on fibers, building construct MXene multiple loss paths, achieving ultra‐wideband absorption of 25.3–1200 GHz in a thickness of 1.8 mm, while also exhibiting superhydrophobicity, acid and alkali resistance, and bending resistance ...
Min Luo, Zihao Chen, Haotian Li, Kexun Li, Wei Wang, Weishi Jiao, Donghong Wang, Qiye Wen   +7 more
wiley   +1 more source

The Ambon Forward Observation Line Strategy 1941-1942 A Lesson in Military Incompetence

, 2010
In October 1940 and in February 1941, the Australian Chiefs of Staff agreed to supply a task force (Gull Force) and an air strike group to garrison the small Dutch Island of Ambon.
Evans, David
core   +1 more source

Pathogen‐Centric Activation of an Azoreductase‐Responsive Antibody‐Antibiotic Conjugate for the Targeted Eradication of MRSA

Advanced Science, EarlyView.
A pathogen‐centric antibody‐antibiotic conjugate (AZO‐AAC) releases antibiotics via bacterial azoreductase, independent of host‐lysosomal function. This mechanism achieves nanomolar eradication of both planktonic and intracellular methicillin‐resistant Staphylococcus aureus (MRSA).
Qi Cheng, Lianqi Liu, Chenghua Liu, Fei Xie, Jingwen Dong, Xiaoyu Qin, Shunxiang Huang, Xian Li, Xingyuan Kou, Hongbin Deng, Jiannan Feng, Wu Zhong, Dian Xiao, Xinbo Zhou   +13 more
wiley   +1 more source

Sulfated Cyclocarya Paliurus Polysaccharide Sorchestrates the Gut Microbiome to Mobilize a Host‐Derived 12‐HEPE Against Ulcerative Colitis

Advanced Science, EarlyView.
A sulfated polysaccharide (SCP) from Cyclocarya paliurus alleviates ulcerative colitis by reshaping the gut microbiome. This remodeled microbiota orchestrates the upregulation of the host‐derived lipid 12‐HEPE, which directly inhibits the TLR4/NF‐κB pathway to suppress inflammation.
Xianxiang Chen, Mingyue Shen, Rui Zhang, Zhibing Huang, Hui Niu, Qiang Yu, Yi Chen, Xiangwen Pan, Liyuan Rong, Huiliang Wen, Jun Yang, Jianhua Xie   +11 more
wiley   +1 more source