Results 141 to 150 of about 134,836 (268)

Advances and perspectives in animal models of human hepatitis A virus

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Following HAV infection, humans, non‐human primates, and Ifnar1−/− mice develop characteristic manifestations of hepatitis A, including fecal viral shedding, elevated serum ALT levels, and inflammatory cell infiltration in the liver. In contrast, HAV‐infected human liver chimeric mice exhibit fecal viral shedding but do not develop clinical features of
Jian Li   +3 more
wiley   +1 more source

Military 'live tissue trauma training' using animals in the U.S. : its purpose, importance and commentary on military medical research and the debate on use of animals in military training

open access: yes, 2012
This article highlights the importance of military training in life saving techniques and treatments developed through clinical research and now used by physicians and combat medics operating in the emergency arena of warfare.
Martinic, Gary (R19006)
core  

Identification and validation of fecal complement component 3 and fibronectin as potential biomarkers for monitoring disease activity in ulcerative colitis based on a mouse model

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study demonstrated elevated levels of fecal component 3 (C3) and fibronectin (FN) in an ulcerative colitis (UC) mouse model. Importantly, fecal C3 exhibited a stronger correlation with disease activity than the clinically used fecal calprotectin (FC).
Yangyun Guo   +6 more
wiley   +1 more source

Computing the Laws of War: Investigating the Relationship between War, International Law and Military Computer Technology

open access: yes
This article proposes the use of conceptual resources from science and technology studies to historicise and investigate co-constitution of the laws of war and military computer technology, with a particular focus on the law’s development in the ...
McKenzie, Simon
core   +1 more source

A mouse model of mechanical stress injury to the basal ganglia using thermosensitive PNIPAM hydrogel for intracerebral hemorrhage research

open access: yesAnimal Models and Experimental Medicine, EarlyView.
In this study, we established a novel mouse model of intracerebral hemorrhage (ICH) by stereotactically injecting thermosensitive PNIPAM hydrogel into the internal capsule to impose localized mechanical stress on the corticospinal tract, which provides a straightforward and reproducible tool for preclinical studies on focal mechanical stress–induced ...
Mingxi Li   +11 more
wiley   +1 more source

Embedding Chemistry and Pharmacy Into Sustainability

open access: yesAngewandte Chemie International Edition, EarlyView.
Chemistry and pharmacy provide products and processes that are indispensable for our high living standard. To understand their relationship with sustainability is important to allow them to contribute to sustainability in a sustainable manner. An integrated overview of green, circular, and sustainable chemistry and pharmacy is given and how they have t
Klaus Kümmerer
wiley   +1 more source

Exploring the cranial morphology and possible convergences of Triassic non‐crocodylomorph pseudosuchians (Archosauria: Pseudosuchia) with other sauropsids through linear morphometrics

open access: yesThe Anatomical Record, EarlyView.
Abstract Triassic pseudosuchians had highly diversified cranial morphologies. These archosaurs occupied diverse ecological roles, ranging from terrestrial predators and herbivores to semiaquatic ambush predators and possible waders. Here, we apply linear cranial morphometrics to assess possible convergences with other sauropsids from the clades ...
Rafael Terras   +3 more
wiley   +1 more source

Revertant Mosaicism Obscures Long‐Awaited Molecular Confirmation of Diamond‐Blackfan Anemia

open access: yes
American Journal of Medical Genetics Part A, EarlyView.
Nicholas A. Borja, Mustafa Tekin
wiley   +1 more source

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