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Cancer‐Associated Fibroblasts Promote Glucose Metabolic Reprogramming and Progression of Triple‐Negative Breast Cancer via Exosomal circFAD104‐Mediated Intercellular Communication

Advanced Science, EarlyView.
CAF‐derived exosomes deliver circFAD104 into TNBC cells, where it acts as a molecular scaffold that bridges the E3 ligase MARCHF8 and PGM1, promoting MARCHF8‐mediated K48‐linked ubiquitination and proteasomal degradation of PGM1. Loss of PGM1 redirects glucose‐phosphate flux from glycogen synthesis toward glycolysis, thereby driving stemness, EMT, and ...
Lei Wang +16 more
wiley +1 more source

A zero-shot prompt learning approach on fine-grained text classification. [PDF]

Sci Rep
Zhang Z, Ge L, Hu R, Wang Y.
europepmc +1 more source

Making sense of shaky data in humanitarian crises. [PDF]

Front Public Health
Colombo S, Altare C.
europepmc +1 more source

Navigating crisis: teleconsultation use and its determinants among internally displaced persons in wartime Sudan. [PDF]

BMC Health Serv Res
Mahgoub EAA, Nouri M.
europepmc +1 more source

Justice Before Pluriversality-A Response to Jecker et al. [PDF]

J Bioeth Inq
Lederman Z.
europepmc +1 more source

Public opinion on civil war in the USA as of mid-2024: findings from a nationally representative survey. [PDF]