Results 31 to 40 of about 8,696,980 (259)

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Effect of Holder pasteurization on nutrient and immune component retention in human milk: a comparison between water and dry pasteurizers

International Breastfeeding Journal
Background Holder pasteurization (HoP; 62.5 °C, 30 min) is the method used most frequently in human milk banks to reduce the risk of infection transmission through donor human milk (DHM), but it has the disadvantage of potentially affecting the contents ...
Miori Tanaka, Midori Date, Kasumi Takayama, Nagisa Matsuura, Katsumi Mizuno   +4 more
doaj   +1 more source

Human Milk Oligosaccharide 2′-Fucosyllactose Improves Innate and Adaptive Immunity in an Influenza-Specific Murine Vaccination Model

Frontiers in Immunology, 2018
BackgroundHuman milk is uniquely suited to provide optimal nutrition and immune protection to infants. Human milk oligosaccharides are structural complex and diverse consisting of short chain and long chain oligosaccharides typically present in a 9:1 ...
Ling Xiao, Thea Leusink-Muis, Nienke Kettelarij, Nienke Kettelarij, Ingrid van Ark, Bernadet Blijenberg, Nienke A. Hesen, Bernd Stahl, Saskia A. Overbeek, Saskia A. Overbeek, Johan Garssen, Johan Garssen, Gert Folkerts, Belinda van’t Land, Belinda van’t Land   +14 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

New latex agglutination assay for the determination of lactoferrin in human milk

International Breastfeeding Journal
Background Lactoferrin (LF) in human milk has various biological properties and contributes to the prevention of preterm birth complications. Enzyme-linked immunosorbent assay (ELISA) is one of the most commonly used methods to measure LF in human milk ...
Miori Tanaka, Midori Date, Katsumi Mizuno   +2 more
doaj   +1 more source

Breastfeeding patterns in cohort infants at a high-risk fetal, neonatal and child referral center in Brazil: a correspondence analysis

BMC Pediatrics, 2020
Background To investigate the prevalence and patterns of breastfeeding at discharge and in the first six months of life in a high-risk fetal, neonatal and child referral center.
Maíra Domingues Bernardes Silva, Raquel de Vasconcellos Carvalhaes de Oliveira, José Ueleres Braga, João Aprígio Guerra de Almeida, Enirtes Caetano Prates Melo   +4 more
doaj   +1 more source

Human milk – facts and myths [PDF]

, 2017
Breast milk is the most suitable nourishment for a newborn. After birth, the mammary glands produce colostrum, which is rich in proteins (including immunoglobulins).
Marta Herman, Marta Sałamacha, Herman, Marta, Sałamacha, Marta, Zygmunt Zdrojewicz, Ewa Starostecka, Starostecka, Ewa, Zdrojewicz, Zygmunt   +7 more
core   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Emergency response and preparedness among Polish human milk banks: a comparison of the COVID-19 pandemic and the 2022 Ukrainian refugee crisis

Frontiers in Nutrition
IntroductionIn recent years, Poland has faced two major emergencies: the COVID-19 pandemic, a global-scale public health emergency in 2020, and the outbreak of a full-scale war in Ukraine, which forced over 9 million Ukrainians–mostly women and children ...
Małgorzata Gawrońska, Małgorzata Gawrońska, Elena Sinkiewicz-Darol, Elena Sinkiewicz-Darol, Elena Sinkiewicz-Darol, Aleksandra Wesołowska, Aleksandra Wesołowska   +6 more
doaj   +1 more source

Milk and Oral Health

, 2011
Oral health includes freedom from disease in the gums, the mucosa and the teeth. There has been a striking reduction in dental caries and periodontitis in industrialized countries, although the proportion with severe disease has remained at 10-15%, and ...
Ingegerd Johansson, Johansson, Ingegerd,, Lif Holgerson, Pernilla,, Pernilla Lif Holgerson   +3 more
core   +1 more source