Results 41 to 50 of about 8,696,980 (259)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Current and future use of donor human milk in hospitals: data from polish human milk banks

International Breastfeeding Journal
Background Donor human milk (DHM) is the recommended alternative when a mother’s own milk is unavailable or insufficient, especially for preterm and ill infants.
Małgorzata Witkowska-Zimny, Melania Majewska, Aleksandra Mołas, Gabriela Olędzka, Aleksandra Wesołowska, representatives of the network of human milk banks in Poland “MILKNET”   +5 more
doaj   +1 more source

Gastrointestinal-active oligosaccharides from human milk and functional foods [PDF]

, 2011
Keywords: human milk oligosaccharides (HMOs), galacto-oligosaccharides (GOS), konjac glucomannan (KGM), breast milk, baby feces, gastrointestinal metabolization, blood-group specific conjugates, CE-LIF-MSn Oligosaccharides, as present in human milk ...
Albrecht, S.A.
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Assessment of the knowledge of female students of the Medical University of Warsaw regarding the prevention of HPV infections

Pielęgniarstwo XXI Wieku, 2022
ASSESSMENT OF THE KNOWLEDGE OF FEMALE STUDENTS OF THE MEDICAL UNIVERSITY OF WARSAW REGARDING THE PREVENTION OF HPV INFECTIONS Introduction. According to the WHO, the health consequences of HPV infections constitute a serious public health problem.
Kinga Kalita-Kurzyńska, Aneta Duda-Zalewska   +1 more
doaj   +1 more source

Time-dependent alterations of soluble and cellular components in human milk

, 2010
This study sought to determine the chronobiological variations in soluble and cellular components of human breast milk. The material was collected from 36 mothers at three stages of maturity - 3 days (colostrum), 10 days (transitional milk) and 30 days ...
Nicomedes, Tathianne dos Reis, Tathianne dos Reis Nicomedes, Iracema de Mattos Paranhos Calderon, Adenilda Cristina Honorio França, Eduardo Luzía França, Calderon, Iracema de Mattos Paranhos [UNESP], Franca, Eduardo Luzia, Honorio Franca, Adenilda Cristina, Calderon, Iracema de Mattos Paranhos   +8 more
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Receiving screened donor human milk as part of a community‐based lactation support programme reduces parental symptoms of anxiety and depression

Maternal and Child Nutrition
Infant feeding decisions and maternal mental health are closely tied. Donor human milk (DHM) protects premature infant health and development and can reduce hospital stays.
Amy Brown, Sam Griffin, Gillian Weaver, Natalie Shenker   +3 more
doaj   +1 more source

Enhanced versus standard fortification of pasteurized donor human milk for growth in very low birth weight infants: a randomized controlled trial

Frontiers in Nutrition
IntroductionVery-low-birthweight (VLBW) infants on pasteurized donor human milk (PDHM) have poorer growth compared to infants on fortified mother's milk, suggesting that standard fortification methods for PDHM are inadequate.MethodsWe designed a ...
Chengsi Ong, Anng Anng Wong, Siew Tin Wong, Ying Zheng, Cynthia Pui Chan Pang, Cynthia Pui Chan Pang, Pooja Agarwal Jayagobi, Pooja Agarwal Jayagobi, Joo Guan Yeo, Joo Guan Yeo, Joo Guan Yeo, Kee Thai Yeo, Kee Thai Yeo, Mei Chien Chua, Mei Chien Chua, Mei Chien Chua   +15 more
doaj   +1 more source

Does neonatal ankyloglossia interfere in the growth of infants during the first 6 months of life? A case series nested in a cohort study

Journal of Medical Case Reports, 2022
Background Ankyloglossia is commonly reported as one of the major causes of breastfeeding difficulty. There is a lack of research on infant growth and latching performance with clinical measures.
Christyann Lima Campos Batista, Alex Luiz Pozzobon Pereira   +1 more
doaj   +1 more source