Results 151 to 160 of about 27,159 (290)

Caracterización parcial de una proteinasa coagulante de la leche aislada del alcaucil (Cynara scolymus L., Asteraceae) [PDF]

open access: yes, 1997
The presence of proteinases in Cynara scolyrnus L. ( artichoke ) has been investigated by determining the proteolytic and milk clotting activities of crude extracts of different parts of the inflorescence in various stages of development, as well as of ...
Brutti, Cristina B.   +3 more
core  

Lactate Metabolism‐Immune Regulation‐Related Gene Signature in Lower‐Grade Gliomas: Prognostic Model Development and Immune Characterization

open access: yesThe FASEB Journal, Volume 40, Issue 6, 31 March 2026.
Lactate metabolism‐immune regulation‐related gene signature (PLA2G2A, TNFRSF12A, VAV3) predicts glioma prognosis. PLA2G2A promotes ECM remodeling, tumor‐associated inflammation, and EMT, leading to enhanced proliferation, invasion, and unfavorable outcomes.
Enhao Zhang   +7 more
wiley   +1 more source

Milk-clotting or Blood-coagulating Activities of Some Proteinases and their Substrate Specificities

open access: yesJournal of the agricultural chemical society of Japan, 1965
インシュリンB鎖に対する基質特異性の判明している数種の蛋白分解酵素について,凝乳および凝血作用を測定し,それらの活性と基質特異性との間に関連性があるかどうかを検討した.凝乳作用はインシュリンB鎖のフェニルアラニンをC-端とするペプチド結合の開裂能力を欠く酵素にはその活性を検出しえなかったが,フェニルアラニン・ペプチド開裂能力と凝乳作用とは必ずしも一致しなかった.一方,凝血作用はインシュリンB鎖に対してトロンビンと同じ特異性を示す酵素のうちトリプシンにわずかの活性を認めたが,他は全く活性を示さなかった.以上より,諸種蛋白分解酵素の凝乳,凝血作用とインシュリンB鎖に対する基質特異性とは必ずしも関連しないと結論した.
openaire   +2 more sources

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, Volume 20, Issue 3, Page 823-837, March 2026.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Irradiated Tumor Cell‐Derived Microparticles Activate Systemic Anti‐Tumor Immunity via the STING/NLRP3/GSDMD Axis in Neutrophils

open access: yesAdvanced Science, Volume 13, Issue 16, 18 March 2026.
Radiotherapy induces tumor cells to release microparticles (RT‐MPs) into the circulation. The mitochondrial DNA carried by these RT‐MPs activates the STING/NLRP3/GSDMD axis in splenic neutrophils, triggering IL‐1β secretion. This, in turn, enhances dendritic cell function and facilitates the formation of cytotoxic T lymphocytes, thereby promoting ...
Yan Hu   +18 more
wiley   +1 more source

CGRP Enhances the Regeneration of Bone Defects by Regulating Bone Marrow Mesenchymal Stem Cells Through Promoting ANGPTL4 Secretion by Bone Blood Vessels

open access: yesAdvanced Science, Volume 13, Issue 14, 9 March 2026.
CGRP interacts with HMEC‐1 by binding to surface receptors, influencing the downstream FAK/AKT/VEGF signaling pathway, and promoting the secretion of ANGPTL4 from vascular endothelial cells into the bone microenvironment. This, in turn, regulates the differentiation of BMSCs into osteoblasts, thus promoting bone formation. ABSTRACT Bone angiogenesis is
Qiong Lu   +9 more
wiley   +1 more source

Foodborne Staphylococcus Aureus: Identification and Enterotoxin Production in Milk and Cheese. [PDF]

open access: yes, 2012
Onemocnění z potravin (alimentární onemocnění) vyvolaná bakteriemi jsou stále aktuálním tématem v celosvětovém měřítku. Abychom zajistili výrobu zdravotně nezávadných potravin, je potřeba nových poznatků o virulenci patogenů, které by doplnily již známé ...
Hrušková, Vendula
core  

Empowering Carbon Fibers With Ti3C2Tx MXene: A Paradigm Shift Toward Integrated Structure‐Function Composites

open access: yesAdvanced Science, Volume 13, Issue 16, 18 March 2026.
This review comprehensively outlines how Ti3C2Tx MXene transforms carbon fiber from a structural component into a multifunctional platform. We systematically detail cutting‐edge modification strategies and showcase exceptional performance in EMI shielding, energy storage, smart sensing, and beyond.
Hongshuo Cao   +6 more
wiley   +1 more source

Regulation of Choroid Plexus Bicarbonate Transporters Following Intraventricular Hemorrhage in Mice

open access: yesCell Biochemistry and Function, Volume 44, Issue 3, March 2026.
ABSTRACT Posthemorrhagic hydrocephalus is a severe complication to intraventricular hemorrhage. The condition results in enlarged brain ventricles and increased intracranial pressure due to accumulation of cerebrospinal fluid (CSF). In this study, two mouse models of intraventricular hemorrhage were investigated: injection of lysed red blood cells ...
Laura Øllegaard Johnsen   +5 more
wiley   +1 more source

Comparative Bioequivalence and Safety Evaluation of Ibuprofen/Phenylephrine Hydrochloride Fixed‐Dose Combination Tablets in Healthy Chinese Volunteers

open access: yesClinical Pharmacology in Drug Development, Volume 15, Issue 3, March 2026.
Abstract This single‐center, randomized, open‐label bioequivalence program compared two fixed‐dose combination (FDC) tablets containing ibuprofen (200 mg) and phenylephrine hydrochloride (10 mg) from different manufacturers in healthy Chinese adults under fasting and fed conditions. A three‐period, partially replicated crossover design was used for the
Menghan Ye   +8 more
wiley   +1 more source

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