Results 161 to 170 of about 6,179,746 (234)

A Novel IDO1/NE Dual Inhibitor, IMM‐H018 Prevents the Primary and Secondary Sepsis and Ameliorates the Kidney Injury Through Inhibiting the Cytokine Storm and Microthrombosis, and Reversing Immunosuppression

open access: yesAdvanced Science, Volume 13, Issue 55, 5 October 2026.
IMM‐H018, a dual IDO1/NE inhibitor, demonstrates potent therapeutic efficacy in sepsis by simultaneously targeting excessive inflammation and immune dysfunction. It prevents both primary and secondary sepsis through anti‐inflammatory, immune‐restoring, and renoprotective mechanisms, reducing organ damage, improving immune homeostasis, preserving kidney
Yi Zhou   +11 more
wiley   +1 more source

Intermittent Fasting Restores Cardiac Lipid Homeostasis in Diabetic Cardiomyopathy in Association With Akkermansia Muciniphila and 1‐methyl‐L‐histidine

open access: yesAdvanced Science, Volume 13, Issue 55, 5 October 2026.
Intermittent fasting reshapes the gut microbiota in diabetic cardiomyopathy, restoring Akkermansia muciniphila and the microbiota‐associated metabolite 1‐methyl‐L‐histidine. This shift is linked to improved cardiac lipid homeostasis, reduced lipid peroxidation, and attenuated myocardial injury, highlighting a gut microbiota–metabolite–lipid axis in ...
Kaiyuan Jiang   +7 more
wiley   +1 more source

Harnessing <i>Levilactobacillus brevis</i> as a Microbial Nanofactory for the Sustainable Production of Multifunctional Silver Nanoparticles. [PDF]

open access: yesInt J Nanomedicine
Hassan MG   +7 more
europepmc   +1 more source

Culture‐Negative Infective Endocarditis Presumed due to Brucella Causing Rapid Native Aortic Valve Destruction in a Young Adult: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Culture‐negative endocarditis with features consistent with Brucella can rapidly destroy a normal aortic valve in young adults. 2023 Duke‐ISCVID criteria (clinical/imaging findings plus histopathology), supported by serology and occupational exposure enabled urgent combined antimicrobial‐surgical management without culture confirmation ...
Baraa Nassar   +5 more
wiley   +1 more source

Scrub Typhus Meningoencephalitis With Concurrent Brucellosis in Rural Nepal: Diagnostic Challenges With Negative PCR in a Low‐Resource Setting

open access: yesClinical Case Reports, Volume 14, Issue 10, October 2026.
Scrub typhus meningoencephalitis with concurrent Brucellosis. ABSTRACT Scrub typhus is an important cause of acute febrile illness in Nepal and can rarely present with meningoencephalitis and multiorgan involvement. We report a 32‐year‐old female farmer from rural Nepal who presented during the monsoon season with high‐grade fever, myalgia, vomiting ...
Pashupati Pokharel   +6 more
wiley   +1 more source

Sustainable Recovery of Actinidin From Actinidia deliciosa Peel Using Biocompatible Cholinium‐Based Ionic Liquids

open access: yesChemistry–Methods, Volume 6, Issue 10, October 2026.
Kiwifruit peel was valorized as a source of actinidin through extraction with aqueous cholinium‐based ionic liquids. Biomolecule recovery was supported by molecular docking, which clarified the role of IL–protein interactions in extraction performance.
Carolina M. Saúde   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy