Results 71 to 80 of about 27,159 (290)

A Glucose‐Responsive Intelligent Antibacterial and Oxygen‐Producing Hydrogel Promotes the Healing of Diabetic Wounds by Regulating Cellular Heterogeneity

open access: yesAdvanced Science, EarlyView.
We have developed a glucose‐triggered on‐demand drug delivery CF‐CPGaMPN hydrogel based on borate ester bonds. It inactivates microbes, releases oxygen, and enables on‐demand drug release in high‐glucose environments to promote healing of diabetic wounds. Single‐cell sequencing reveals that the CF‐CPGaMPN hydrogel significantly alleviates dysfunctional
Manxuan Liu   +8 more
wiley   +1 more source

Clay-Catalyzed Ozonation of Hydrotalcite-Extracted Lactic Acid Potential Application for Preventing Milk Fermentation Inhibition

open access: yesMolecules, 2022
An unprecedented route for mitigating the inhibitory effect of lactic acid (LA) on milk fermentation was achieved through lactate adsorption on hydrotalcite (Ht) from simulated lactate extracts.
Meriem El Baktaoui   +7 more
doaj   +1 more source

Applications of plasma-liquid systems : a review [PDF]

open access: yes, 2019
Plasma-liquid systems have attracted increasing attention in recent years, owing to their high potential in material processing and nanoscience, environmental remediation, sterilization, biomedicine, and food applications.
De Geyter, Nathalie   +4 more
core   +1 more source

Decoding the Cardiac Immune Microenvironment and Fibroblast Crosstalk in Radiotherapy Combined with Immunotherapy‐Induced Cardiac Fibrosis Based on Single‐Cell Transcriptomic Analysis

open access: yesAdvanced Science, EarlyView.
This study highlights that radioimmunotherapy drives crosstalk between fibroblasts and immune cells (especially macrophages) in the cardiac microenvironment, with IL‐6 as the key mediator, and tocilizumab alleviates cardiac fibrosis by targeting this interplay.
Yuxi Luo   +10 more
wiley   +1 more source

Isolation and production optimization of a novel milk-clotting enzyme Bacillus velezensis DB219

open access: yesAMB Express, 2022
The milk-clotting enzyme (MCE) is a crucial ingredient in cheese manufacture. Due to the limits of traditional MCE, finding viable substitute is a pressing issue. This study aims to isolate and identify a wild strain with high milk-clotting activity (MCA)
Yao Zhang   +6 more
doaj   +1 more source

New markers of bulk milk quality in relation to mastitis [PDF]

open access: yes, 2009
All dairy processors depend on a continuous supply of high-quality bulk milk from milk producers to be able to distribute liquid milk and dairy products.
Wickström, Erik
core  

ZBTB21 Is a Dual Suppressor of Pyroptosis and MHC‐I Antigen Presentation That Promotes Tumor Immune Evasion

open access: yesAdvanced Science, EarlyView.
ZBTB21 is a transcription factor that epigenetically suppresses pyroptosis and MHC‐I antigen presentation, enabling tumor immune evasion. Genetic ablation of ZBTB21 activates pyroptotic cell death and enhances antigen presentation, recruiting CD8+ T cells to overcome immune checkpoint blockade resistance.
Lei Zhao   +12 more
wiley   +1 more source

Nanotherapeutic Macrophage‐Neuro Reprogramming Through Immunometabolic Crosstalk Mitigates Sepsis‐Induced Lung Injury and Neurologic Damage

open access: yesAdvanced Science, EarlyView.
SJNPs co‐deliver JHU083 and spermine to reprogram macrophage–neuron immunometabolic crosstalk in sepsis. By suppressing pro‐inflammatory M1 polarization and promoting NGF‐mediated neurotrophic signaling, SJNPs preserve pulmonary neuronal integrity, alleviate lung injury, and improve survival in murine sepsis models.
Wenhui Wang   +11 more
wiley   +1 more source

PRODUCTION OF HIGH LEVELS OF TRANSGENC FACTOR IX WITHOUT GENE RESCUE, AND ITS THERAPEUTIC USES [PDF]

open access: yes, 2011
A non-human transgenic mammalian animal, as described above, contains an exogenous double stranded DNA sequence stably integrated into the genome of the animal, which comprises cis-acting regulatory units operably linked to a DNA sequence encoding human ...
Cooper, Julian D.   +2 more
core   +1 more source

Expression and purification of recombinant human coagulation Factor VII fused to His-Tag through Gateway technology [PDF]

open access: yes
Background. Factor VII is a plasma glycoprotein that participates in the coagulation process leading to generation of fibrin. Construction, expression and purification of recombinant FVII fused to poly histidin tag through gateway technology ...
حلبیان, راحله   +6 more
core   +1 more source

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