Results 81 to 90 of about 57,754 (290)

Osmotic Tension Asymmetry Drives Electrotactic Migration via PDLIM7‐Polarized Microfilament Coordination in Breast Cancer Cells

Advanced Science, EarlyView.
This study establishes an electric field‐induced directional migration model using fluorescence tension probes to visualize microfilament forces and intracellular osmotic pressure dynamics in the electrotactic migration of breast cancer cells. This model delineates how electromechanical interactions among membrane potential, ion channels, OP, traction ...
Ling Zhu, Zihui Zheng, Wang Li, Chenyi Shou, Ying Zhao, Lijun Zhang, Xiaoli Shi, Yunfeng Hu, Huanhuan Zhao, Huiwen Wu, Jun Guo   +10 more
wiley   +1 more source

Halorotetin B, A Novel Terpenoid Compound Derived from Marine Ascidian, Suppresses Tumor Growth by Targeting the Cell Cycle Regulator UBE2C

Advanced Science, EarlyView.
Halorotetin B, a novel small‐molecule terpenoid identified from an edible marine ascidian, exhibits strong anti‐tumor activity both in vitro and in vivo through direct targeting UBE2C to induce tumor cell cycle arrest and then lead tumor cell senescence. As a newly discovered UBE2C inhibitor, Halorotetin B can serve as a novel potential cell senescence
Shanhao Han, Jianhui Li, Yuting Zhu, Penghui Liu, Yaoyao Zheng, Muchun He, Bo Dong   +6 more
wiley   +1 more source

Donation barriers, enablers, patterns and predictors of milk bank donors in the United States and United Kingdom

Maternal and Child Nutrition
Pasteurised donor human milk is recommended for very low birthweight infants who do not have access to their mother's milk. Although the use of donor milk continues to increase, little is known about the donation experiences of milk bank donors. We aimed
Bruna Gutierrez dosSantos, Natalie Shenker, Gillian Weaver, Maryanne T. Perrin   +3 more
doaj   +1 more source

Promotion of breasfeeding on human milk banks of Rio De Janeiro

Revista de Enfermagem da Universidade Federal de Santa Maria, 2015
Aim: to describe the care practice of health professionals to support breastfeeding in Human Milk Banks of Rio de Janeiro. Method: descriptive, exploratory and qualitative study in five Human Milk Banks, with participation of twenty five health ...
Maria Bertilla Lutterbach Riker Branco, Valdecyr Herdy Alves, Diego Pereira Rodrigues, Rosangela de Mattos Pereira de Souza, Amanda Fernandes do Nascimento da Cruz, Tuâny Figueiredo Marinho   +5 more
doaj   +1 more source

Microbiological Safety of Banked Human Milk: Current Status and Future Directions

, 2021
Marie-Pierre Cayer and Danny Brouard*
openalex   +1 more source

Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1

Advanced Science, EarlyView.
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang, Yi Liu, Zhiying Yao, Haolong Lai, Xiaoxin Chen, Ziqiu Wang, Yiqiong Bao, Tingting Li, Xiaoming Zhou, Xiabin Chen, Peiguo Yang   +10 more
wiley   +1 more source

Bacillus cereus strains from donor human milk and hospital environment: uncovering a putative common origin using comparative analysis of toxin and infra-red spectroscopy profiles

AIMS Microbiology, 2023
Bacillus cereus is reported as a common cause of toxin-induced food poisoning and of contamination in pasteurized human milk donations. As various toxins can be produced by B.
Gaëtan Outurquin, Odile Obin, Anaïs Petit , Roxane Weiss, André Léké , Crespin Adjidé , Catherine Mullié   +6 more
doaj  

Gabpα‐Pparγ Complex Determines Glycolytic Capacity and Lactic Acid Homeostasis in Brown Fat

Advanced Science, EarlyView.
This study identifies the Gabpα–Pparγ complex as a key transcriptional regulator that couples glycolysis to lactate‐driven thermogenesis in brown adipose tissue by directly activating Eno1 transcription. ‌Competitive disruption of this interaction impairs lactate metabolism and thermogenic capacity.
Zhihan Wang, Huanyu Wang, Qianqian Kang, Ruping Pan, Rui He, Min Yang, Jiadai Liu, Xuemin Peng, Yuyu Xie, Hongyan Deng, Wenshe Wang, Zengzhe Zhu, Jing Ge, Yulian Liu, Ronghui Gao, Yaming Guo, Peng Yu, Limeng Pan, Danpei Li, Pema Maretich, Xiaoping Luo, Xuefeng Yu, Yong Chen   +22 more
wiley   +1 more source

Biomimetic Nanomedicine for Senescence‐Modulated Immune Activation Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A multifunctional mPDZM nanoplatform is developed in this study. mPDZM integrates chemotherapy‐induced senescence, selective senolysis, and STING‐mediated immune activation. mPDZM effectively clears senescent tumor cells, remodels the tumor immune microenvironment, and enhances antitumor T‐cell responses.
Shiji Fang, Liyun Zheng, Bin Lin, Jiale Chen, Dehai Hou, Yiming Ding, Mengzhu Han, Pan Qin, Mengyuan Wang, Xiaoju Guo, Yeyu Zhang, Gaofeng Shu, Fazong Wu, Jianfei Tu, Minjiang Chen, Zhongwei Zhao, Zhuang Liu, Jiansong Ji   +17 more
wiley   +1 more source

Setting up the first human milk bank in Uganda: a success story from Nsambya hospital

Frontiers in Nutrition
BackgroundThe World Health Organization (WHO) strongly recommends the use of donor human milk (DHM) for low birth weight infants when mother’s own milk is unavailable or insufficient. However, the use of DHM requires the availability of human milk banks (
Victoria Nakibuuka, Janat Kainza, Ritah Nasiima, Sanyu Nalunga, Ritah Nazziwa, Hamim Mponye, Christinah Nuwahereza, Ronald Kyambadde, Racheal Nantenza, Caroline Nassonko, Barbara Nalubwama, Immaculate Nabwami, Madrine Nabaliira, Cleophas Kabategweta, Olivia Nalule, Joannita Nampijja, Barbara Namugga, Peter Kirabira, Gillian Weaver   +18 more
doaj   +1 more source