Results 121 to 130 of about 1,591,321 (343)

Who are the donors? A characterisation of two years of volunteer milk donors to a community-based UK milk bank [PDF]

open access: green, 2023
Sophie Wedekind   +5 more
openalex   +1 more source

CD103+ T Cells Eliminate Damaged Alveolar Epithelial Type II Cells Under Oxidative Stress to Prevent Lung Tumorigenesis

open access: yesAdvanced Science, EarlyView.
This work unravels a novel function of CD103+ T cells in eradicating oxidative‐stressed somatic cells to prevent lung tumorigenesis and identifies specific CD103+ T cell‐decline as a key feature in the aged lung. This comprehensive study highlights the contribution of immuno‐dysregulation to the high incidence of aging‐associated lung cancers ...
Yu Xu   +7 more
wiley   +1 more source

Extending the Reach of Human Milk Banking

open access: yesWorld Nutrition, 2017
The banking of human milk is expanding rapidly in both high- and low-income countries. Most milk banks serve critically ill infants, including those who are born prematurely or have low birthweight.
George Kent
doaj   +1 more source

Plasma amino acids in preterm infants fed different human milk diets from a human milk bank [PDF]

open access: bronze, 2007
Sandra Christo dos Santos   +3 more
openalex   +1 more source

AntiBMPNN: Structure‐Guided Graph Neural Networks for Precision Antibody Engineering

open access: yesAdvanced Science, EarlyView.
AntiBMPNN, a deep learning framework that integrates antibody‐specific 3D data, MPNN, frequency‐based scoring, and AlphaFold 3, achieves superior antibody sequence design. In most cases, it outperforms ProteinMPNN, AntiFold, and AbMPNN in CDR design, demonstrating higher binding affinities and sequence recovery.
Ze‐Yu Sun   +13 more
wiley   +1 more source

A Feedback Loop Between Fatty Acid Metabolism and Epigenetics in Clear Cell Renal Carcinoma

open access: yesAdvanced Science, EarlyView.
The current study has profiled the landscape of active enhancers in ccRCC and identified FABP5 as an oncogene. FABP5 is essential for the lipid droplet formation driven by HIFs and critical for H3K27ac and enhancer activity. The study has discovered the function of a feedback loop between epigenetics and lipid metabolism regulated by FABP5 in ccRCC ...
Zhou Ye   +21 more
wiley   +1 more source

Functionalized Biomimetic Nanoparticles Targeting the IL‐10/IL‐10Rα/Glycolytic Axis in Synovial Macrophages Alleviate Cartilage Degeneration in Osteoarthritis

open access: yesAdvanced Science, EarlyView.
The MOF material UIO‐66‐NH2 is functionalized with DBCO groups on its surface, encapsulating NO‐prednisolone and conjugating it with azide‐modified IL‐10. Finally, the complex is extruded with MM to form biomimetic functional nanoparticles. Upon intra‐articular injection, MI@UN, enveloped by the MM, specifically targets synovial macrophages, is ...
Wenwei Li   +10 more
wiley   +1 more source

Perceptions of community-based human milk banks before and after training in a resource-limited South African setting

open access: yes, 2016
Background. Human breastmilk provides gold standard nutrition and immunological support to infants. For low birth weight, HIV-infected, HIV-exposed or otherwise vulnerable babies, it can mean the difference between life and death.
H. Goodfellow   +3 more
semanticscholar   +1 more source

Lysosomal Cathepsin S Escape Facilitates Near Infrared Light‐Triggered Pyroptosis Via an Antibody‐Indocyanine Green Conjugate

open access: yesAdvanced Science, EarlyView.
ICAM1 antibody‐bound ICG triggers tumor‐specific, caspase‐1‐independent pyroptosis via CTSS‐mediated GSDMD cleavage, activates antitumor immunity, and synergizes with anti–PD‐1 therapy, offering a non‐apoptotic strategy to overcome resistance in cancer treatment.
Fan Chen   +17 more
wiley   +1 more source

Evaluation of Human Milk Banks Paraná- Br: a Comparative Study [PDF]

open access: bronze, 2012
Anelise Ludmila Vieczorek   +1 more
openalex   +1 more source

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