Results 171 to 180 of about 1,575,590 (368)
Exploration, EarlyView.An acid‐cleavable Tf‐modified engineering exosome‐based brain‐targeting delivery system (ACTE) was proposed using metabolic glycoengineering and bioorthogonal click chemistry, enabling co‐delivery of siTGF‐β and DOX for GBM treatment. ACTE was featured by higher BBB transcytosis efficiency and hierarchical targeting delivery to GBM cells.
Jun Yang +14 more
wiley +1 more source
Brain Pathology, Volume 33, Issue 1, January 2023., 2023 In this study Cooper‐Knock et al identified an autosomal dominant ALS pedigree associated with p.Y374X‐TARDBP. In patient tissue the authors confirmed reduced TDP‐43 protein expression, abnormal TDP‐43 fragmentation and deficient TDP‐43‐mediated splicing. This work extends the phenotypes associated with TDP‐43 mutations.
Johnathan Cooper‐Knock +17 more
wiley +1 more source
MiCull2 -- simulating mastitis transmission through milking order [PDF]
arXivContagious mastitis pathogens can be transmitted through milking. However, previously published simulation models, such as MiCull, have not directly taken this into account. We have reimplemented the MiCull model to model transmission of contagious mastitis pathogens through milking in a milking parlor. This additional complexity requires a substantial
arxiv
Determination of Dornic Acidity as a Method to Select Donor Milk in a Milk Bank [PDF]
, 2012 Sara Vázquez‐Román +5 more
openalex +1 more source
Exploration, EarlyView.Ticagrelor nanoparticles modified platelets could adhere to tumor‐associated platelets by specific recruiting ability and responsively release ticagrelor under MMPs stimulation. The released ticagrelor could inhibit platelets activity, enhancing tumor treatment efficacy.
Qi Lu +12 more
wiley +1 more source
Brain Pathology, Volume 33, Issue 1, January 2023., 2023 Schematic depicting characterization of pathological tau signatures and nuclear alterations in neurons, astrocytes and microglia in neurodegenerative diseases. Abstract Accumulation of pathological tau aggregates is a prominent feature in tauopathies that leads during the course of the diseases to neuronal dysfunction before and cell death after ...
Mauro Montalbano +4 more
wiley +1 more source
Evaluation of Human Milk Banks Paraná- Br: a Comparative Study [PDF]
, 2012 Anelise Ludmila Vieczorek +1 more
openalex +1 more source
Berries: Health Effects via Modulation of the Gut Microbiota
Food Frontiers, EarlyView.ABSTRACT Berries are widely regarded as beneficial foods, rich in polyphenols, flavonoids, and other bioactive compounds that could positively influence human health. Although the gut microbiota plays a crucial role in metabolism and physiology of humans, the interaction between berries and human gut microbiota activity remains unclear.
Manjin Xu +11 more
wiley +1 more source