Results 231 to 240 of about 1,716,846 (311)

Notoginsenoside‐Fa mitigates vascular endothelial permeability via targeting SUGT1 to stabilize NLRP3 in a resting state

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Notoginsenoside‐Fa (Noto‐Fa) is an emerging active compound derived from notoginseng with promise in treating cardiovascular diseases. The development of cardiovascular diseases is intricately linked to the damage of vascular endothelium and it is widely acknowledged that numerous chronic inflammation pathways, especially the ...
Xiao‐Ying Yu   +9 more
wiley   +1 more source

The amino terminal domain of the human α7 nicotinic acetylcholine receptor subunit leads to the functional expression of human/insect receptors

open access: yesBritish Journal of Pharmacology, EarlyView.
Human α7 receptors have been characterised in terms of pharmacological properties. Insertion of the N‐terminal domain of the human α7 subunit leads to honeybee and cockroach chimeric receptors activated by ACh and inhibited by α‐Bgt. Insertion of the human cys‐loop leads to cockroach chimeric receptors modulated by PNU.
Alison Cartereau   +9 more
wiley   +1 more source

Discovery of a Novel γ‐Glutamylcyclotransferase Inhibitor Plumbagin by Luminescence‐Based High‐Throughput Screening

open access: yesCancer Science, EarlyView.
A cell‐based high‐throughput screening system utilizing the luminescent probe LISA‐103 was developed to monitor γ‐glutamylcyclotransferase (GGCT) activity in cancer cells. Through this assay, plumbagin was identified as a novel GGCT inhibitor that induces cell cycle arrest and suppresses cancer cell growth. ABSTRACT γ‐Glutamylcyclotransferase (GGCT) is
Keiko Taniguchi   +10 more
wiley   +1 more source

Impact of Transnational Family Separation on Parenting and Psychosocial Well‐Being for Black African Migrant Parents in Hamilton

open access: yesChild &Family Social Work, EarlyView.
ABSTRACT In light of increased migration from sub‐Saharan Africa (SSA) to Hamilton in the past 5 years, this qualitative study explores the experiences of Black African migrant parents resettling in Hamilton, Canada. Using semi‐structured interviews and thematic analysis, four key themes emerged: (1) impact of migration and family separation stress on ...
Tsinat Semagn   +3 more
wiley   +1 more source

Human milk banking services: An umbrella review protocol. [PDF]

open access: yesHRB Open Res
O'Donovan R   +8 more
europepmc   +1 more source

Environmentally adjusted productivity growth and shadow prices for dairy farms

open access: yesCanadian Journal of Agricultural Economics/Revue canadienne d'agroeconomie, EarlyView.
Abstract We estimate the environmentally adjusted productivity growth and shadow price for Ontario dairy farms. We use an input‐oriented directional distance function and farm‐level data from 2000 to 2020. First, we find that while GHG emissions per cow increase with higher milk yields, emission intensity decreases as milk yield per cow increases.
Bibek Dahal   +2 more
wiley   +1 more source

A Framework for Evaluation of New Processing Technologies in Human Milk Banking. [PDF]

open access: yesCompr Rev Food Sci Food Saf
Clifford V   +5 more
europepmc   +1 more source

Climate shocks, coping strategies, and household resilience: Evidence from a three‐wave panel in Malawi

open access: yesContemporary Economic Policy, EarlyView.
Abstract Climate shocks threaten rural livelihoods in Malawi, yet households adopt diverse coping strategies to mitigate welfare losses. Using three‐wave Living Standards Measurement Study–Integrated Surveys on Agriculture panel data (2013–2019) and household fixed‐effects models, this study examines how climate shocks affect food security and ...
Suyeon Ro, Jongwook Lee
wiley   +1 more source

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