Results 251 to 260 of about 189,951 (342)

Comparative Lipid Profiles of Milk Bank Breast Milk and Infant Formulas [PDF]

open access: gold, 2013
Anya Oleynik   +2 more
openalex   +1 more source

An antisense oligonucleotide targeting the heat‐shock protein HSPB5 as an innovative therapeutic approach in pulmonary fibrosis

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Idiopathic pulmonary fibrosis (IPF) is a fatal disease characterized by fibroblast activation and abnormal accumulation of extracellular matrix in the lungs. We previously demonstrated the importance of the heat shock protein αB‐crystallin (HSPB5) in TGF‐β1 profibrotic signalling, which suggests that HSPB5 could be a new ...
Pierre‐Marie Boutanquoi   +17 more
wiley   +1 more source

Tryptophan Metabolic Enzyme IL4I1 Inhibits Ferroptosis by Decreasing Ubiquitination of Nrf2 via I3P in Glioblastoma

open access: yesCell Proliferation, EarlyView.
Interleukin 4‐induced 1 (IL4I1) is a novel anti‐ferroptosis regulator‐IL4I1 by regulating Nrf2 and serving as a ROS scavenger in glioblastoma multiforme (GBM). In addition, the ubiquitination of Nrf2 could be attenuate by indole‐3‐pyruvic acid binding with Nrf2 directly.
Yang Xu   +10 more
wiley   +1 more source

Ezh2 Regulates Early Astrocyte Morphogenesis and Influences the Coverage of Astrocytic Endfeet on the Vasculature

open access: yesCell Proliferation, EarlyView.
Ezh2‐deficient astrocytes showed morphologically more slender but sparse dendrites, resulting in reduced endfoot coverage and also causing disruption of the blood–brain barrier. ABSTRACT Astrocytes are crucial for central nervous system (CNS) development and function, with their differentiation being stringently controlled by epigenetic mechanisms ...
Xinghua Zhao   +9 more
wiley   +1 more source

YTHDC1 Modulates the Osteogenic Capacity of hPDLSCs via Wnt/β‐Catenin Signalling Pathway for the Treatment of Bone Defects in Osteoporosis Rats

open access: yesCell Proliferation, EarlyView.
In this study, human periodontal ligament stem cells (hPDLSCs) were successfully isolated and cultivated from the periodontal ligament tissues of healthy premolar teeth. Our in vivo experiments demonstrated that YTHDC1 augmented the osteogenic differentiation capacity of these cells via the Wnt/β‐catenin signalling pathway.
Dan Tan   +8 more
wiley   +1 more source

Visions of Community Health and the Social Good in Kenya: Turning Community Health Workers into Entrepreneurs

open access: yesDevelopment and Change, EarlyView.
ABSTRACT In East Africa, social enterprises that fuse development work with entrepreneurial activities and a language of ‘innovation’ are becoming prominent. Critical of the NGO/donor model, which they hold as unsustainable, such organizations are funded by corporate investment and philanthropic capital but aim for self‐reliance through enlisting local
Edwin Ambani Ameso, Ruth Jane Prince
wiley   +1 more source

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