Results 111 to 120 of about 404,929 (263)

Spatiotemporal Multi‐Omic Mapping Reveals Liver‐Muscle Metabolic Crosstalk in Cancer Cachexia

Advanced Science, EarlyView.
The interactive CCAtlas platform delineates cross‐species, spatiotemporal, and sex‐specific molecular dynamics and metabolic rewiring across organs during cancer cachexia. Hepatic Gamt downregulation curtails hepatic creatine synthesis to trigger systemic creatine insufficiency and consequent skeletal muscle atrophy in LLC tumour‐bearing mice ...
Zihan Tian, Qianyu Wang, Wenyan Gao, Xianfeng Li, Jiawen Fan, Xiaoliang Wu, Siqi Liu, Xiangdong Ming, Danna Yeerken, Mutian Shen, Qingjie Min, Qimin Zhan, Yan Wang   +12 more
wiley   +1 more source

Milk Production and Climate Variability in a High-Andean Dairy System: A Longitudinal Case Study. [PDF]

Animals (Basel)
Montenegro-Arellano GF, Carvajal-Pérez LA, Urgilés-Urgilés GP, Quishpe-Sinailin PD, Herrera-Lana AE.   +4 more
europepmc   +1 more source

YTHDC1 Orchestrates Glucose and Glutamate Rewiring to Overcome Lethal Metabolic Stress in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Lai et al. find that m6A reader YTHDC1 is specifically overexpressed in triple‐negative breast cancer (TNBC) and orchestrates glucose and glutamine metabolism in an m6A‐dependent manner to confer robust adaptability to lethal metabolic stress. Leveraging YTHDC1 knockdown‐induced metabolic vulnerability, an ATF4 mRNA‐targeted nanotherapy is developed to
Zheng‐Hao Lai, Yi Wang, Na‐Na Li, Ling Zeng, Renzhong Liu, Xue Li, Cheukfai Li, Xin‐Yu Ma, Wenkui Fu, Yingsen Tang, Jinjin Chen, Ning Liao, Man‐Li Luo   +12 more
wiley   +1 more source

Accuracy of genomic prediction for milk production traits in Mehsana buffalo. [PDF]

Front Genet
Patel MR, Patel AC, Joshi RS, Patel DV, Nayee N, Sudhakar A, Jakhesara SJ, Koringa PG.   +7 more
europepmc   +1 more source

Water‐Soluble POSS Promotes Concurrent Coalescence and Crosslinking for Multiscale‐Reinforced, Coalescent‐Free Waterborne Coatings

Advanced Science, EarlyView.
Water‐soluble amine‐functionalized polyhedral oligomeric silsesquioxane promotes concurrent latex coalescence and crosslinking, allowing epoxy‐functional particles to form continuous films without added volatile coalescing agents. The resulting multiscale‐reinforced waterborne coatings combine high strength, toughness, optical transparency, scratch ...
Chao Wang, Bin Wu, Lin Li, Yibo Ru, Xiaohe Zhang, Minlong Wang, Ruoyan Yang, Jie An   +7 more
wiley   +1 more source

Effects of the Temperature-Humidity Index on Milk Production Traits and Gene-Environment Interactions in Chinese Holstein Cows. [PDF]

Animals (Basel)
Ou K, Zheng K, Teng J, Li Y, Zhang Q, Ning C, Wang D.   +6 more
europepmc   +1 more source

AHR‐Responsive Carbon Dots Orchestrate Skin Wound Healing and Colonic Mucosal Repair via Treg‐Mediated Macrophage Efferocytosis

Advanced Science, EarlyView.
Guided by pharmacophore modeling and molecular docking, aryl hydrocarbon receptor (AHR)‐responsive carbon dots were synthesized. They bind directly to AHR and expand gut‐resident regulatory T (Treg) cells. Treg‐derived C‐C motif chemokine ligand 1 (CCL1) enhances macrophage efferocytosis, creating a pro‐regenetative niche that promotes colonic mucosal ...
Zilu Zhu, Han Zhang, Shuai Lin, Wenqian Zheng, Xin Li, Xiaowei Xu, Ruili Yang   +6 more
wiley   +1 more source

Effects of palmitic acid and high oleic acid soybeans on milk production of high-producing dairy cows. [PDF]

JDS Commun
Bales AM, Ribeiro Pinheiro Coelho V, Lock AL.   +2 more
europepmc   +1 more source

DLST Succinylation‐Mediated Mitochondrial Metabolic Remodeling and Cuproptosis Resistance Promote Malignant Progression of Lung Adenocarcinoma

Advanced Science, EarlyView.
The DLST K409 succinylation mediated by CPT1A promotes OXPHOS and redox homeostasis through regulating enzyme activity, thereby promoting the malignant progression of LUAD. Notably, the succinylation of DLST can enhance the cuproptosis resistance by inhibiting its lipoylation.
Xuanxuan Li, Peijun Zhou, Xingzhi Peng, Qixin Liu, Wenhui Zeng, Rui Wang, Liangfang Shen, Jinwu Peng, Qin Zhou, Lifang Yang   +9 more
wiley   +1 more source

Ruminant Species Composition and Reported Methane Intensity in Global Milk Production: A 186-Country Decomposition Under Alternative Allocation Boundaries. [PDF]

Animals (Basel)
Ketney O.
europepmc   +1 more source