Results 181 to 190 of about 466,277 (313)

Effect of Somatic Cell Count on Milk Production, Composition, Colour, Coagulation Properties and Cheese-Making Ability Traits in Manchega Dairy Sheep. [PDF]

Foods
Heddi I, Caballero-Villalobos J, Amalfitano N, Martínez F, Cantarero-Aparicio MÁ, Cecchinato A, Ramón M, Garzón A, Arias R.   +8 more
europepmc   +1 more source

Cuproptosis and Mitophagy Mediated by the THUMPD1/IGF2R‐Dependent Suppression of AKT and Activation of AMPK Signaling Suppress Lung Adenocarcinoma Progression

Advanced Science, EarlyView.
THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu, Bo Qin, Zhuoyu Gu, Weizheng Ding, Xiaoming Chen, Kaishang Zhang, Yujin Qiao, Shuang Yuan, Song Zhao, Xiangnan Li, Peng Zhang   +10 more
wiley   +1 more source

Influence of Animal Feeding on Milk Supply in Navarre

Determining the competitive position of dairy farms depends on several technological, economic and institutional variables. Among them, are remarkable those related to animal feeding in the current context of high variability on prices.
Aldanondo, Ana Maria, Casasnovas, Valero L.   +1 more
core  

Genetic Evaluation of Milk Production Traits in the Serbian Saanen Goat Population. [PDF]

Animals (Basel)
Zeljić Stojiljković K, Mićić N, Bogdanović V, Đedović R, Pihler I, Stojiljković N, Stanojević D.   +6 more
europepmc   +1 more source

Small Extracellular Vesicles‐Derived Circ6718 Unlocks Stromal Remodeling and Serves as a Biomarker in Gastric Cancer

Advanced Science, EarlyView.
sEVs‐circ6718 serves as a promising serum biomarker for gastric cancer early diagnosis and prognosis, promoting malignant transformation in gastric cancer cells and GC‑MSC differentiation into CAFs. sEVs‑circ6718 holds potential as a biomarker for the early diagnosis and prognostic assessment of gastric cancer.
Fan Zhang, Xueyan Zang, Dongli Wang, Rong Li, Hui Qian, Wenrong Xu, Jiajia Jiang, Yongmin Yan   +7 more
wiley   +1 more source

A Review of Milk Production in Pakistan with Particular Emphasis on Small-scale Producers

The purpose of the study is to assess the economics of dairy farming in Pakistan and the prospects for improving the dairy income for small-scale producers, which currently form the backbone of the dairy industry.
Mahmood, Kalid, Garcia, Otto, Hemme, Torsten   +2 more
core  

GWAS Reveals Key Candidate Genes Associated with Milk-Production in Saanen Goats. [PDF]

Animals (Basel)
Li F, He Y, Yan H, Bu J, Wang Z, Xu X, Li D, Cao B, An X.   +8 more
europepmc   +1 more source

β‐Elemene Rescues Radiation‐Induced Enteritis by Orchestrating a Host‐Microbiome Circuit That Fuels Epigenetic DNA Repair

Advanced Science, EarlyView.
This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He, Jiapeng Bao, Shukang Deng, Weijie Zang, Haoming Yan, Zihao Zhao, Guangze Zhang, Ruiqing Liu, Junjie Chen, Yilin Hu, Wanjiang Xue   +10 more
wiley   +1 more source

Effects of zinc supplementation on milk production performance and growth status of Bactrian camels. [PDF]

Front Vet Sci
Zhou X, Jiang M, Amjad M, Khosbileg, Liu M, Wu Z, Cheng J, Tang J, Xu L, Zhu X, Yang L, Hua G.   +11 more
europepmc   +1 more source

Pharmacologic Modulation of ARID3A with Rimegepant Reactivates Type I Interferon Signaling and Sensitizes Triple‐Negative Breast Cancer to PD‐1 Blockade

Advanced Science, EarlyView.
This study identifies ARID3A as a key immunosuppressive transcription factor in TNBC. Its inhibition activates the type I IFN pathway, boosting CD8+ T cell infiltration and sensitizing tumors to anti‐PD‐1. The FDA‐approved migraine drug Rimegepant targets ARID3A, enhances immunotherapy efficacy in preclinical models, and establishes a druggable axis to
Teng Zhou, Yifei Zhu, Cheng Zeng, Jinlu Han, Huiying Huang, Doudou Li, Mingxi Lin, Yizi Jin, Qin Guo, Yuxin Yan, Xinhui Mao, Yifei Zhou, Jian Zhang   +12 more
wiley   +1 more source