Results 191 to 200 of about 466,277 (313)

GEOGRAPHIC CHANGES IN U.S. DAIRY PRODUCTION

open access: yes
Changes in quantities of milk marketed are analyzed by spatial econometrics using the county-level data, to provide statistical explanations of the recent major geographic shifts in U.S. dairy production.
Peterson, Hikaru Hanawa
core  

Enhancing CAR‐T Cell Efficacy in Solid Tumors by Inhibiting CCL5/VEGF‐Mediated Angiogenesis

open access: yesAdvanced Science, EarlyView.
This study reveals that CAR‐T cells in solid tumors produce CCL5, which paradoxically induces VEGF and angiogenesis to promote tumor growth. Blocking CCL5/VEGF signaling—through gene knockout, or the CCR5 inhibitor maraviroc—significantly enhances the antitumor efficacy of CAR‑T therapy (the diagram was created in Biorender).
Shishuo Sun   +15 more
wiley   +1 more source

Quantifying Economic Losses due to Milk Fever in Dairy Farms

open access: yes
Milk fever, a metabolic disease, affects dairy animals usually within one or two days after calving, resulting in a huge reduction in milk production and thus becomes economically most important.
Thirunavukkarasu, M.   +3 more
core  

A Circuit of Mechanically Regulated Transcription Factors Balances Regenerative and Fibrotic Memory of Mesenchymal Stromal Cells

open access: yesAdvanced Science, EarlyView.
Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi   +7 more
wiley   +1 more source

RECENT CHANGES IN THE REGIONAL STRUCTURE OF U.S. DAIRY PRODUCTION

open access: yes
Gauging the impact of recent policy changes, this article analyzes production characteristics and the impact of the dairy assessment for northeastern dairy farmers as compared to other major production regions.
Huy, Birgit   +2 more
core  

Comparison of K-Means and Hierarchical Clustering Methods for Buffalo Milk Production Data. [PDF]

open access: yesAnimals (Basel)
Trapanese L   +5 more
europepmc   +1 more source

Epithelial TRIM27 Inhibits Intestinal Inflammation in Ulcerative Colitis by the USP7/TRIM27‐IKK Double Negative‐Feedback

open access: yesAdvanced Science, EarlyView.
ABSTRACT The E3 ubiquitin ligase tripartite motif 27 (TRIM27) is a negative regulator of NF‐κB activation and the innate immune response, and TRIM27 deficiency significantly impairs dextran sulfate sodium (DSS)‐induced colitis. The function of TRIM27 in intestinal epithelial cells (IECs), the mechanism by which TRIM27 inhibits the NF‐κB pathway and its
Weimin Xu   +10 more
wiley   +1 more source

Marketing of Milk in Various Agro-climatic Zones of Jammu and Kashmir

open access: yes
The study has examined the prevailing marketing system, utilization, marketed surplus / consumption, channels of distribution, processing / demand and supply scenario of milk in Jammu and Kashmir. The study is based on the primary data collected from 150
Wani, S.A., Wani, M.H.
core  

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