Results 21 to 30 of about 62,735 (259)

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

Mensuração dos custos e avaliação de rendas em sistemas de produção de leite caprino nos Cariris Paraibanos Calculation of the costs and evaluation of incomes in different systems of production of goat milk in Cariris Paraibanos

Revista Brasileira de Zootecnia, 2010
Objetivou-se mensurar o custo de produção do leite e avaliar a renda na atividade caprina por sistemas de produção. Os sistemas de produção estão localizados na microrregião dos Cariris Paraibanos e foram definidos por critérios de eficiência técnica e ...
Hélio Luiz Beretta Dal Monte, Roberto Germano Costa, Evandro Vasconcelos Holanda Júnior, Edgard Cavalcanti Pimenta Filho, George Rodrigo Beltrão da Cruz, Marcos Paulo Carrera Menezes   +5 more
doaj   +1 more source

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

Advanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo, Nguyen Thi Nguyen, LiLi Guo, Ngoc Man Phan, Hyunsu Shin, Tae‐il Kim, Yu Seok Youn, Jaeyun Kim   +7 more
wiley   +1 more source

Milk Prices and Cost of Milk Production

Journal of Dairy Science, 1920
The present study pertains to the seasonal cost of producing milk for direct consumption. Numerous organizations in various parts of the United States have made from time to time many studies of the cost of mil]~ production, but in most instances these data involve what is known as the year cost of milk production. Little or no attention has been given
openaire   +1 more source

Smarter Sensors Through Machine Learning: Historical Insights and Emerging Trends across Sensor Technologies

Advanced Functional Materials, EarlyView.
This review highlights how machine learning (ML) algorithms are employed to enhance sensor performance, focusing on gas and physical sensors such as haptic and strain devices. By addressing current bottlenecks and enabling simultaneous improvement of multiple metrics, these approaches pave the way toward next‐generation, real‐world sensor applications.
Kichul Lee, Osman Gul, Yeongjae Kwon, Jaeseok Jeong, Seokjoo Cho, Jihyeon Ahn, Jehee Yu, Cheolmin Kim, Donho Lee, Hyeonseok Han, Byeongju Lee, Jungrak Choi, Ji‐Hwan Ha, Yongrok Jeong, Kyungnam Kang, Ali Javey, Junseong Ahn, Inkyu Park   +17 more
wiley   +1 more source

Projected heat stress challenges and abatement opportunities for U.S. milk production.

PLoS ONE, 2019
Cost-effective heat mitigation strategies are imperative for maintaining milk production and dairy farm profitability in the U.S. with projected climate change.
Kpoti M Gunn, Michael A Holly, Tamie L Veith, Anthony R Buda, Rishi Prasad, C Alan Rotz, Kathy J Soder, Anne M K Stoner   +7 more
doaj   +1 more source

Sustainable Catalyst‐Free PLG Networks: Recyclability, Biodegradability, and Functional Performance

Advanced Functional Materials, EarlyView.
A catalyst‐additive free covalent adaptable network is developed from star‐shaped poly(lactide‐co‐glycolide) cross‐linked with pyromellitic dianhydride, enabling internal carboxylic acid‐driven transesterification. The resulting biodegradable network exhibits mechanical robustness (Young's modulus ≈1.6 GPa), complete recyclability, rapid biodegradation
Lars Schwarzer, Emilia Fulajtar, Seema Agarwal   +2 more
wiley   +1 more source

Economic and social structures of water buffalo farming in Muş province of Turkey

Revista Brasileira de Zootecnia
The purpose of this study was to analyse the socio-economic structure of water buffalo farming in the province of Muş, in Turkey. The stratified sampling method was used to calculate sample size of buffalo farms in the Central, Korkut, and Hasköy ...
Mehmet Işik, Mevlüt Gül
doaj   +1 more source

Risk Based Milk Pricing Model at Dairy Farmers Level

Media Peternakan, 2017
The milk price from a cooperative institution to farmer does not fully cover the production cost. Though, dairy farmers encounter various risks and uncertainties in conducting their business.
W. Septiani, Marimin Marimin, Y. Herdiyeni, L. Haditjaroko   +3 more
doaj   +1 more source

Membrane Vesicles from Lacticaseibacillus Casei BL23 Exhibit Antimicrobial Activity Against Escherichia coli and Immunostimulatory Effects on Human Peripheral Blood Mononuclear Cells

Advanced Healthcare Materials, EarlyView.
Membrane vesicles derived from the probiotic Lacticaseibacillus casei BL23 demonstrate antimicrobial properties against Escherichia coli and a potential biological effect in improving the overall survival of C. elegans infected with Pseudomonas aeruginosa. These vesicles stimulated immune responses in primary cells without causing toxicity. Our results
Cecilia L. D'Antoni, Leila Pourtalebi Jahromi, Lorenzo Sana, Ana Paula Domínguez Rubio, Maja Dorfner, Jennifer Munkert, Heike Danzer, Philipp Arnold, Mikhail Lebedev, Esther Zanin, Oscar E. Pérez, Gregor Fuhrmann   +11 more
wiley   +1 more source