Results 251 to 260 of about 5,802,592 (350)
Advanced Science, EarlyView.This study reveals that the E3 ubiquitin ligase TRIM56 exacerbates neuronal ferroptosis and brain damage by mediating K48‐linked ubiquitination and degradation of KLF4, leading to suppression of the xCT/GSH/GPX4 axis. Targeting TRIM56 alleviates cerebral ischemia‐reperfusion injury in vivo and in vitro, highlighting its therapeutic potential.
Qiangping Wang +15 more
wiley +1 more source
Advanced Science, EarlyView.Phosphorylation of Optineurin by TBK1 induces the formation of filaments that condensate upon binding to linear polyubiquitin. Membrane‐anchored LC3 partitions into these condensates, suggesting that phase separation of filamentous Optineurin with ubiquitylated cargo promotes the sequestration of cargo and its subsequent alignment with LC3‐positive ...
Maria G. Herrera +10 more
wiley +1 more source
Risks of spreading foot and mouth disease through milk and dairy products
, 1997 Alex Donaldson
openalex +2 more sources
Advanced Science, EarlyView.By engaging in different active exploration behaviors, the tactile perception system can generate distinct signal modes, enabling the application of targeted decoding strategies for efficient and accurate perception of both external and internal object features.
Yuanzhi Zhou +8 more
wiley +1 more source
Standards and labeling of milk fat and spread products in different countries
, 2017 Chia-Lin Lee +8 more
openalex +1 more source
Advanced Science, EarlyView.This research deciphers the m6A transcriptome by profiling its sites and functional readout effects: from mRNA stability, translation to alternative splicing, across five different cell types. Machine learning model identifies novel m6A‐binding proteins DDX6 and FXR2 and novel m6A reader proteins FUBP3 and L1TD1.
Zhou Huang +11 more
wiley +1 more source
Bioactive Peptides from Milk and Dairy Products: Applications and Activities
Pınar Güner
openalex +2 more sources
Alkyltriphenylphosphonium Binding to Cardiolipin Triggers Oncosis in Cancer Cells
Advanced Science, EarlyView.Alkyltriphenylphosphonium, exemplified by TPP+‐C14, preferentially accumulates in mitochondria and selectively binds to cardiolipin, a key phospholipid of the inner mitochondrial membrane, causing loss of mitochondrial membrane potential, severe cellular ATP depletion, and calcium imbalance.
Jin Li +8 more
wiley +1 more source