Results 61 to 70 of about 936,581 (316)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Microorganisms, 2022 This study aimed to investigate whether agricultural by-products with a high NDF content and small-particle-size substitute for forage could cause hindgut acidosis and dysbacteriosis in lactating dairy cows. We investigated the impact of soybean hull and
Jiaying Lyu +6 more
doaj +1 more source
Content of fatty acids, vitamin E and carotenoids in milk and herbage as affected by sward composition and period of grazing [PDF]
, 2011 The quality of organic milk is affected by feed composition, and especially the high use of legumes has been identified as the reason for high levels of polyunsaturated fatty acids, carotenoids and tocopherols in organic milk. Four different pastures
Eriksen, J. +5 more
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Understanding Critical Factors and Antecedents in Indonesian Small Dairy Industries [PDF]
, 2019 Small dairy farmers in Indonesia typically join dairy cooperatives in order to overcome the limited resources in maintaining fresh dairy products, especially milk. The higher the quality, the better the price paid by milk processing companies.
Mulyono, Nur Budi +2 more
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Heat stress on calves and heifers: a review
Journal of Animal Science and Biotechnology, 2020 The current review is designed with aims to highlight the impact of heat stress (HS) on calves and heifers and to suggest methods for HS alleviation. HS occurs in animals when heat gain from environment and metabolism surpasses heat loss by radiation ...
Jingjun Wang +7 more
doaj +1 more source
Haptoglobin and serum amyloid A in relation to the somatic cell count in quarter, cow composite and bulk tank milk samples [PDF]
, 2007 Milk somatic cell count (SCC) is the gold standard in diagnosis of subclinical mastitis, and is also an important parameter in quality programmes of dairy cooperatives.
Persson Waller, Karin +2 more
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FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
The day‐to‐day stability of the ruminal and fecal microbiota in lactating dairy cows
MicrobiologyOpen, 2020 In this study, we examined differences between the microbiota of the ruminal fluid (DR) and feces (DF) from five lactating dairy cows over three consecutive days using 16S rRNA gene sequence‐based analysis.
Shuai Huang +7 more
doaj +1 more source
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source